A Novel Leucyl-tRNA Synthetase Inhibitor, MRX-6038, Expresses Anti-Mycobacterium abscessus Activity In Vitro and In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00601-22
Abstract: Therapeutic options for Mycobacterium abscessus infections are extremely limited, and new drugs are needed. The anti-M. abscessus activity of MRX-6038, ABSTRACT Therapeutic options for Mycobacterium abscessus infections are extremely limited, and new drugs are needed.… read more here.
Keywords: mrx 6038; mrx; mycobacterium abscessus; abscessus activity ... See more keywords
Omadacycline, Eravacycline, and Tigecycline Express Anti-Mycobacterium abscessus Activity In Vitro
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00718-23
Abstract: The antimicrobial activities of four third-generation tetracycline-class drugs, omadacycline (OMC), eravacycline (ERC), tigecycline (TGC), and sarecycline (SAC), were determined for 193 M. abscessus isolates. The activities of the four drugs at two different temperatures (30°C… read more here.
Keywords: tgc; tigecycline; abscessus activity; abscessus ... See more keywords
Sitafloxacin Expresses Potent Anti-Mycobacterium abscessus Activity
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.779531
Abstract: Therapeutic options for treating Mycobacterium abscessus infections are extremely limited; quinolones are important. The in vitro anti-M. abscessus activities of nine quinolones, emphasizing sitafloxacin, were investigated. Antimicrobial susceptibility testing was performed on 10 non-tuberculous mycobacterium… read more here.
Keywords: mycobacterium abscessus; abscessus activity; sitafloxacin; abscessus ... See more keywords