Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88.
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DOI: 10.1016/j.celrep.2017.05.059
Abstract: The underlying mechanism by which MyD88 regulates the development of obesity, metainflammation, and insulin resistance (IR) remains unknown. Global deletion of MyD88 in high-fat diet (HFD)-fed mice resulted in increased weight gain, impaired glucose homeostasis,… read more here.
Keywords: cd11c macrophages; insulin resistance; dectin; absence myd88 ... See more keywords