Absence of p21(WAF1/CIP1/SDI1) protects against osteopenia and minimizes bone loss after ovariectomy in a mouse model
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DOI: 10.1371/journal.pone.0215018
Abstract: p21(WAF1/CIP1/SDI1) is a critical sentinel of the cell cycle that plays an important role in determining cell fate with respect to proliferation, differentiation and apoptosis. Recent studies have demonstrated that inhibition/loss of p21 promotes osteo-chondro… read more here.
Keywords: absence p21; ovariectomy; bone loss; p21 ... See more keywords