Absent in melanoma 2 regulates tumor cell proliferation in glioblastoma multiforme
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-019-03230-y
Abstract: Inflammation is a key aspect of glioblastoma multiforme (GBM) although it remains unclear how it contributes to GBM pathogenesis. Inflammasomes are intracellular multi-protein complexes that are involved in innate immunity and are activated by cellular… read more here.
Keywords: gbm; glioblastoma multiforme; proliferation; absent melanoma ... See more keywords
Deficiency in Absent in Melanoma (AIM) 2, an Innate Immunity Protein, Is Associated with Hepatic Steatosis
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DOI: 10.2337/db18-2443-pub
Abstract: Absent in Melanoma (AIM) 2, an HIN-200 domain family interferon inducible gene, is a cytosolic sensor for double-stranded DNA, forms the AIM2 inflammasome, and is a tumor suppressor gene. Lack of AIM2 increases the risk… read more here.
Keywords: protein; none; absent melanoma; melanoma aim ... See more keywords
Absent in Melanoma 2 (AIM2) Regulates the Stability of Regulatory T Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23042230
Abstract: Absent in melanoma 2 (AIM2) is a cytosolic dsDNA sensor that has been broadly studied for its role in inflammasome assembly. However, little is known about the function of AIM2 in adaptive immune cells. The… read more here.
Keywords: melanoma aim2; cell; aim2; cd4 ... See more keywords