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Predicting personalised absolute treatment effects in individual participant data meta‐analysis: An introduction to splines

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Published in 2022 at "Research Synthesis Methods"

DOI: 10.1002/jrsm.1546

Abstract: BACKGROUND Modelling non-linear associations between an outcome and continuous patient characteristics, whilst investigating heterogeneous treatment effects, is one of the opportunities offered by individual participant data meta-analysis (IPD-MA). Splines offer great flexibility, but guidance is… read more here.

Keywords: treatment effects; analysis; meta analysis; absolute treatment ... See more keywords