Slowing down lipolysis significantly enhances the oral absorption of intact solid lipid nanoparticles.
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DOI: 10.1039/c9bm00873j
Abstract: Only a limited amount of orally administered lipid nanoparticles are absorbed as intact particles due to lipolysis by lipases in the gastrointestinal tract. It is hypothesized that by counteracting lipolysis, more particles will survive gastrointestinal… read more here.
Keywords: absorption intact; oral absorption; slns; lipolysis ... See more keywords