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Physiologically Based Absorption Modeling of Salts of Weak Bases Based on Data in Hypochlorhydric and Achlorhydric Biorelevant Media

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Published in 2018 at "AAPS PharmSciTech"

DOI: 10.1208/s12249-018-1059-3

Abstract: Physiologically based absorption modeling has been attracting increased attention to study the interactions of weakly basic drug compounds with acid-reducing agents like proton-pump inhibitors and H2 blockers. Recently, standardized gastric and intestinal biorelevant media to… read more here.

Keywords: based absorption; absorption modeling; biorelevant media; physiologically based ... See more keywords