Weldable, Reprocessable, and Water-resistant Polybenzoxazine Vitrimer Crosslinked by Dynamic Imine Bonds.
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DOI: 10.1002/cssc.202301708
Abstract: Traditional polybenzoxazine thermosets cannot be reprocessed or recycled due to the permanent crosslinked networks. The dynamic exchangeable characteristics of imine bonds can impart the networks with reprocessabilities and recyclabilities. This study reported a weldable, reprocessable,… read more here.
Keywords: abz; polybenzoxazine; reprocessable water; water ... See more keywords
Testing Albendazole Resistance in Fasciola hepatica.
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DOI: 10.1007/978-1-0716-0475-5_16
Abstract: The egg development test is a useful in vitro tool to detect albendazole (ABZ) resistance in Fasciola hepatica. ABZ is the only flukicidal compound with ovicidal activity. The described test is based on the ABZ… read more here.
Keywords: resistance fasciola; fasciola hepatica; hepatica; resistance ... See more keywords
Preparation, Physicochemical Characterization and In Vitro and In Vivo Activity Against Heligmosomoides polygyrus of Novel Oral Formulations of Albendazole and Mebendazole
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.xphs.2020.02.002
Abstract: Abstract Albendazole (ABZ) and mebendazole (MBZ) are the 2 most commonly used drugs in the treatment of soil-transmitted helminth infections in humans, but their performance is hampered by low solubility and physicochemical properties. We developed… read more here.
Keywords: vivo activity; mbz; activity; abz ... See more keywords
Developing epigenetic synergistic drug combinations with albendazole in paediatric acute myeloid leukaemia
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-6788
Abstract: Acute myeloid leukaemia (AML) is an aggressive malignancy that account for ~25% of all paediatric cancers (Tebbi 2021). Over the last few decades, advancements in technologies, earlier diagnosis, better supportive care, and refinements of chemotherapy… read more here.
Keywords: leukaemia; abz; aml; drug ... See more keywords
Effect of Genotype and Sex of the Host on the Bioavailability of Novel Albendazole Microcrystals Based on Chitosan and Cellulose Derivatives
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DOI: 10.1208/s12249-020-01692-2
Abstract: Albendazole (ABZ), an anthelmintic compound widely used in the treatment of systemic nematode infections, is included in the list of class II drugs based on the Biopharmaceutical Classification System. ABZ has limited effectiveness due to… read more here.
Keywords: genotype sex; microcrystals based; bioavailability; cbi ... See more keywords
Improvement of Antialveolar echinococcosis efficacy of novel Albendazole-Bile acids Derivatives with Enhanced Oral Bioavailability
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0011031
Abstract: Alveolar echinococcosis (AE) is a chronic and fatal infectious parasitic disease, which has not been well-researched. Current recommended therapies for AE by the World Health Organization include complete removal of the infected tissue followed by… read more here.
Keywords: microscopy; bioavailability; echinococcosis; efficacy ... See more keywords
Giardia duodenalis: Flavohemoglobin is involved in drug biotransformation and resistance to albendazole
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010840
Abstract: Giardia duodenalis causes giardiasis, a major diarrheal disease in humans worldwide whose treatment relies mainly on metronidazole (MTZ) and albendazole (ABZ). The emergence of ABZ resistance in this parasite has prompted studies to elucidate the… read more here.
Keywords: abz abzso; abz; resistance; drug ... See more keywords
Co-Treatment with Human Leukocyte Extract and Albendazole Stimulates Drug’s Efficacy and Th1 Biased Immune Response in Mesocestoides vogae (Cestoda) Infection via Modulation of Transcription Factors, Macrophage Polarization, and Cytokine Profiles
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15020541
Abstract: The model flatworm Mesocestoides vogae proliferating stage of infection elicits immunosuppression in the host. It was used to investigate the effects of human leukocyte extract (DLE) alone and in combination with anthelmintic albendazole (ABZ) on… read more here.
Keywords: leukocyte extract; infection; via modulation; human leukocyte ... See more keywords
Developing a Formulation Strategy Coupled with PBPK Modeling and Simulation for the Weakly Basic Drug Albendazole
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15041040
Abstract: Albendazole (ABZ) is a weakly basic drug that undergoes extensive presystemic metabolism after oral administration and converts to its active form albendazole sulfoxide (ABZ_SO). The absorption of albendazole is limited by poor aqueous solubility, and… read more here.
Keywords: formulation; pbpk modeling; basic drug; abz ... See more keywords