FSCN1 as a new druggable target in adrenocortical carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34526
Abstract: Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with a high risk of relapse and metastatic spread. The actin‐bundling protein fascin (FSCN1) is overexpressed in aggressive ACC and represents a reliable prognostic indicator. FSCN1 has… read more here.
Keywords: new druggable; druggable target; acc; adrenocortical carcinoma ... See more keywords
Escherichia coli-Based Expression and In Vitro Activity Assay of 1-Aminocyclopropane-1-Carboxylate (ACC) Synthase and ACC Oxidase.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6854-1_5
Abstract: 1-Aminocyclopropane-1-carboxylate (ACC) synthase and ACC oxidase are key enzymes in the ethylene biosynthetic pathway in plant tissues, and in vitro assay of their activities is indispensable for analysis, especially, for studying the action mechanism of… read more here.
Keywords: acc synthase; acc; carboxylate acc; aminocyclopropane carboxylate ... See more keywords
Cellular subtype may predict survival outcomes in salivary adenoid cystic carcinoma patients—a single-institution experience
Sign Up to like & getrecommendations! Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2248-2
Abstract: Adenoid cystic carcinoma (ACC) is a biphasic salivary gland malignancy that is characterized by cellular, morphologic, and clinical heterogeneity [1]. ACCs are the secondmost common salivary gland malignancy, are the most common malignancy of minor… read more here.
Keywords: acc; cystic carcinoma; single institution; cell ... See more keywords
Determinants of variability in management of acute calculous cholecystitis
Sign Up to like & getrecommendations! Published in 2017 at "Surgical Endoscopy"
DOI: 10.1007/s00464-017-5874-5
Abstract: BackgroundWhile evidence supports early compared to delayed cholecystectomy as optimal management of acute calculous cholecystitis (ACC), significant variability in practice remains. The purpose of this study was to identify variables associated with early cholecystectomy, to… read more here.
Keywords: acc; delayed cholecystectomy; early cholecystectomy; management acute ... See more keywords
Utility of Tokyo guidelines and intraoperative safety steps in improving the outcome of laparoscopic cholecystectomy in complex acute calculus cholecystitis: a prospective study
Sign Up to like & getrecommendations! Published in 2020 at "Surgical Endoscopy"
DOI: 10.1007/s00464-020-07905-w
Abstract: Laparoscopic cholecystectomy (LC) in complicated acute calculus cholecystitis (ACC) poses multiple challenges. This prospective, observational study assessed the utility and safety of a set protocol and intraoperative steps in LC for complex ACC. All cases… read more here.
Keywords: acc; safety steps; intraoperative safety; safety ... See more keywords
Stathmin 1 is highly expressed and associated with survival outcome in malignant adrenocortical tumours
Sign Up to like & getrecommendations! Published in 2019 at "Investigational New Drugs"
DOI: 10.1007/s10637-019-00846-9
Abstract: Adrenocortical carcinoma (ACC) is an aggressive endocrine cancer with few molecular predictors of malignancy and survival, especially in paediatric patients. Stathmin 1 (STMN1) regulates microtubule dynamics and has been involved in the malignant phenotype of… read more here.
Keywords: acc; associated survival; highly expressed; stathmin highly ... See more keywords
Adrenocortical carcinoma: presentation and outcome of a contemporary patient series
Sign Up to like & getrecommendations! Published in 2019 at "Endocrine"
DOI: 10.1007/s12020-019-01918-9
Abstract: BackgroundAdrenocortical carcinoma (ACC) is a rare endocrine carcinoma with poor 5-year survival rates of 20 Hounsfield Units (HU) for all tumours (median 34 (21–45)), median size 92 mm (20–196), Ki67 17% (1–40%), Weiss score 7 (4–9) and… read more here.
Keywords: presentation; acc; carcinoma; ensat stage ... See more keywords
Adrenocortical Carcinoma with Hypercortisolism.
Sign Up to like & getrecommendations! Published in 2018 at "Endocrinology and metabolism clinics of North America"
DOI: 10.1016/j.ecl.2018.02.003
Abstract: Adrenocortical carcinoma (ACC) is a rare and aggressive tumor. ACC may be associated with different syndromes of hormone excess, most frequently Cushing's syndrome with or without hypersecretion of androgens. Recent data suggest that cortisol excess… read more here.
Keywords: adrenocortical carcinoma; acc; carcinoma hypercortisolism; endocrinology ... See more keywords
Metastable solubility and local structure of amorphous calcium carbonate (ACC)
Sign Up to like & getrecommendations! Published in 2020 at "Geochimica et Cosmochimica Acta"
DOI: 10.1016/j.gca.2020.06.030
Abstract: Abstract The properties of amorphous calcium carbonate provide the foundation for understanding mineralization of calcified skeletons but inconsistencies between studies suggest the physical picture is incomplete. This study quantifies the metastable solubility and structure of… read more here.
Keywords: calcium carbonate; acc; amorphous calcium; solubility ... See more keywords
Adrenocortical carcinoma (ACC): When and why should we consider germline testing?
Sign Up to like & getrecommendations! Published in 2018 at "Presse medicale"
DOI: 10.1016/j.lpm.2018.07.004
Abstract: Adrenocortical carcinoma (ACC), particularly when occurring during childhood, has been a traditional component of the tumor spectrum of Li-Fraumeni syndrome. Recent research has defined a significant risk increase of ACC with other familial cancer syndromes,… read more here.
Keywords: adrenocortical carcinoma; risk; acc; acc consider ... See more keywords
Preparation and Stability of Monodisperse Amorphous CaCO3 Microspheres of High Hardness and Sphericity.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c03596
Abstract: Using amorphous CaCO3 (ACC) to biomimic the crustacean exoskeleton and optimize the physical and chemical properties of the polymeric phase of ACC holds great promise. Controlling the ACC morphology and stability is key in this… read more here.
Keywords: amorphous caco3; acc; hardness; microspheres high ... See more keywords