Induction of Pancreatic Inflammation Accelerates Pancreatic Tumorigenesis in Mice.
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DOI: 10.1007/978-1-4939-8879-2_25
Abstract: Pancreatitis is a major risk factor for the development of pancreatic cancer. In genetically engineered mouse models, induction of pancreatic inflammation dramatically accelerates oncogenic KRas-induced fibrosis, precancerous PanIN formation, and tumorigenesis. Here we describe simple… read more here.
Keywords: induction pancreatic; tumorigenesis; accelerates pancreatic; inflammation ... See more keywords