LncRNA LINC00968 accelerates the proliferation and fibrosis of diabetic nephropathy by epigenetically repressing p21 via recruiting EZH2.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.08.048
Abstract: Emerging evidence have indicated the vital roles of long noncoding RNAs (lncRNAs) in the pathophysiological process of diabetic nephropathy. However, the deepgoing mechanism that lncRNAs regulate the diabetic nephropathy pathogenesis is still ambiguous. In present… read more here.
Keywords: linc00968 accelerates; proliferation fibrosis; diabetic nephropathy; accelerates proliferation ... See more keywords
A prion accelerates proliferation at the expense of lifespan
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.60917
Abstract: In fluctuating environments, switching between different growth strategies, such as those affecting cell size and proliferation, can be advantageous to an organism. Trade-offs arise, however. Mechanisms that aberrantly increase cell size or proliferation—such as mutations… read more here.
Keywords: prion; growth; prion accelerates; accelerates proliferation ... See more keywords