Valproic acid attenuates sepsis-induced myocardial dysfunction in rats by accelerating autophagy through the PTEN/AKT/mTOR pathway.
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DOI: 10.1016/j.lfs.2019.116613
Abstract: AIMS Sepsis is a leading cause of death and disability worldwide. Autophagy may play a protective role in sepsis-induced myocardial dysfunction (SIMD). The present study investigated whether valproic acid (VPA), a class I histone deacetylase… read more here.
Keywords: sepsis; myocardial dysfunction; valproic acid; induced myocardial ... See more keywords