Glutathione Adduct Patterns of Michael-Acceptor Carbonyls.
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DOI: 10.1021/acs.est.6b04981
Abstract: Glutathione (GSH) has so far been considered to facilitate detoxification of soft organic electrophiles through covalent binding at its cysteine (Cys) thiol group, followed by stepwise catalyzed degradation and eventual elimination along the mercapturic acid… read more here.
Keywords: acceptor carbonyls; adduct; michael acceptor; acceptor ... See more keywords