Michael acceptor containing drugs are a novel class of 5‐lipoxygenase inhibitor targeting the surface cysteines C416 and C418
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2016.11.004
Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Recently, we published that nitro‐fatty acids (NFA) are potent electrophilic molecules which inhibit 5‐lipoxygenase (5‐LO) by interacting catalytically with cysteine residues next to a substrate entry channel. The… read more here.
Keywords: containing drugs; acceptor containing; michael acceptor; acceptor ... See more keywords