Three Birds with One Stone: Acceptor Engineering of Hemicyanine Dye with NIR-II Emission for Synergistic Photodynamic and Photothermal Anticancer Therapy.
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DOI: 10.1002/smll.202204851
Abstract: It is challenging to develop a near-infrared (NIR) small molecular photosensitizer for synergistic phototherapy in deep tissues. Herein, first, a heavy-atom-free NIR hemicyanine photosensitizer (BHcy) for 808 nm light-mediated synergistic photodynamic therapy/photothermal therapy (PDT/PTT) anticancer therapy… read more here.
Keywords: anticancer therapy; synergistic photodynamic; therapy; hemicyanine ... See more keywords
Acceptor engineering of metallacycles with high phototoxicity indices for safe and effective photodynamic therapy
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DOI: 10.1039/d2sc06936a
Abstract: Although metallacycle-based photosensitizers have attracted increasing attention in biomedicine, their clinical application has been hindered by their inherent dark toxicity and unsatisfactory phototherapeutic efficiency. Herein, we employ a π-expansion strategy for ruthenium acceptors to develop… read more here.
Keywords: engineering metallacycles; phototoxicity; metallacycles high; acceptor engineering ... See more keywords