Oxidative Ring Expansion of Cyclobutanols: Access to Functionalized 1,2-Dioxanes.
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DOI: 10.1021/acs.orglett.1c00070
Abstract: Cyclobutanols undergo an oxidative ring expansion with Co(acac)2 and triplet oxygen to give 1,2-dioxanols. The formation of an alkoxy radical drives the regioselective cleavage of the ring on the more substituted side before insertion of… read more here.
Keywords: oxidative ring; ring expansion; cyclobutanols access; expansion cyclobutanols ... See more keywords
Tandem Reaction of Azide with Isonitrile and TMSCnFm(H): Access to N-Functionalized C-Fluoroalkyl Amidine.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00125
Abstract: N-Functionalized C-fluoroalkyl amidines are attracting great attention due to their potential in pharmaceuticals. Herein, we report a Pd-catalyzed tandem reaction of azide with isonitrile and fluoroalkylsilane via a carbodiimide intermediate, providing facile access to N-functionalized… read more here.
Keywords: reaction azide; functionalized fluoroalkyl; access functionalized; azide isonitrile ... See more keywords
Photoredox Catalysis Enables Access to N-Functionalized 2,1-Borazaronaphthalenes.
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DOI: 10.1021/acs.orglett.9b00884
Abstract: The synthesis and utilization of a class of 2,1-borazaronaphthyltrifluoroborate reagents that provide a general solution to the challenge of N-functionalization of the 2,1-borazaronaphthalene core is described. By adorning the nitrogen of this core with a… read more here.
Keywords: functionalized borazaronaphthalenes; enables access; photoredox catalysis; access functionalized ... See more keywords
Access to functionalized luminescent Pt(II) complexes by photoredox-catalyzed Minisci alkylation of 6-aryl-2,2'-bipyridines.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d0cc07307e
Abstract: Photoredox-mediated C-H bond alkylation of 6-aryl-2,2'-bipyridines with N-(acyloxy)phthalimides is reported. The reaction exhibits excellent functional group tolerance, including chiral aliphatic groups. The influence of the incorporated C6'-alkyl group on the photophysical properties of the corresponding… read more here.
Keywords: aryl bipyridines; alkylation aryl; functionalized luminescent; access functionalized ... See more keywords