Abstract 1891: Breaking barriers to access intracellular targets with T-cell engagers: Discovery of diverse, developable, and ultra-specific antibodies against a MAGE-A4 pMHC
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DOI: 10.1158/1538-7445.am2023-1891
Abstract: In this study, we describe the discovery of antibodies against a MAGE-A4 peptide-major histocompatibility complex (pMHC). These antibodies will form the basis for the tumor-binding arm of T-cell engagers (TCEs) against this target. Bispecific CD3… read more here.
Keywords: ultra specific; antibodies mage; access intracellular; diverse developable ... See more keywords