Alternating access mechanisms of LeuT-fold transporters: trailblazing towards the promised energy landscapes.
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DOI: 10.1016/j.sbi.2016.12.006
Abstract: Secondary active transporters couple the uphill translocation of substrates to electrochemical ion gradients. Transporter conformational motion, generically referred to as alternating access, enables a central ligand binding site to change its orientation relative to the… read more here.
Keywords: energy; mechanisms leut; access mechanisms; leut fold ... See more keywords