Isocyanide-Based MCRs: Straightforward Access to Perfluroalkylated γ-Spiroiminolactones
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DOI: 10.1055/s-0037-1610540
Abstract: A variety of perfluoroalkyl-substituted γ-spiroiminolactones have been synthesized via a one-pot, three-component cascade reaction in which isocyanides, methyl perfluoroalk-2-ynoates and 1,2-diketones undergo highly regioselective Michael addition, nucleophilic addition and cyclization. This reaction has the advantages… read more here.
Keywords: perfluroalkyl ated; straightforward access; mcrs straightforward; based mcrs ... See more keywords