Cyclocarbopalladation/Stille Cascade: Stereoselective Access to Quaternary Functionalized Carbons.
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DOI: 10.1021/acs.orglett.1c02400
Abstract: Exploration of the 4-exo-dig cyclocarbopalladation in the discovery of new and original scaffolds afforded some unexpected results. The search for a way to produce seven-membered ring systems led to polycyclic molecules bearing a tetrasubstituted carbon.… read more here.
Keywords: cyclocarbopalladation stille; stille cascade; access quaternary; stereoselective access ... See more keywords
Fe-Catalyzed Alkylazidation of α-Trifluoromethylalkenes: An Access to Quaternary Stereocenters Containing CF3 and N3 Groups.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00439
Abstract: A concise Fe-catalyzed alkylazidation of α-trifluoromethylalkenes via a C-C bond cleavage/radical addition/azidation cascade is described. This protocol features a broad substrate scope, excellent functional group compatibility, and the ability to be performed on a gram… read more here.
Keywords: quaternary stereocenters; trifluoromethylalkenes access; catalyzed alkylazidation; alkylazidation trifluoromethylalkenes ... See more keywords