Expanding Access to Remdesivir via an Improved Pyrrolotriazine Synthesis: Supply Centered Synthesis
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DOI: 10.1021/acs.orglett.0c02848
Abstract: Pyrrolotriazine 1 is an important precursor to remdesivir. Initial results toward an efficient synthesis are disclosed consisting of sequential cyanation, amination, and triazine formation beginning from pyrrole. This route makes use of highly abundant, commoditized… read more here.
Keywords: access remdesivir; supply; expanding access; remdesivir via ... See more keywords