Interrogating the Accessible Chromatin Landscape of Eukaryote Genomes Using ATAC-seq.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1103-6_10
Abstract: The ATAC-seq assay has emerged as the most useful, versatile, and widely adaptable method for profiling accessible chromatin regions and tracking the activity of cis-regulatory elements (cREs) in eukaryotes. Thanks to its great utility, it… read more here.
Keywords: accessible chromatin; atac seq; chromatin; interrogating accessible ... See more keywords
Assay for Transposase Accessible Chromatin (ATAC-Seq) to Chart the Open Chromatin Landscape of Human Pancreatic Islets.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7768-0_11
Abstract: The regulatory mechanisms that ensure an accurate control of gene transcription are central to cellular function, development and disease. Such mechanisms rely largely on noncoding regulatory sequences that allow the establishment and maintenance of cell… read more here.
Keywords: transposase accessible; accessible chromatin; atac seq; chromatin ... See more keywords
Identification of the accessible chromatin regions in six tissues in the soybean.
Sign Up to like & getrecommendations! Published in 2022 at "Genomics"
DOI: 10.1016/j.ygeno.2022.110364
Abstract: Accessible chromatin regions (ACRs) are tightly associated with gene expressions in the genome. Conserved non-coding cis-regulatory elements, such as transcription factor binding motifs, are usually found in ACRs, indicating an essential regulatory role of ACRs… read more here.
Keywords: six tissues; accessible chromatin; chromatin regions; regions six ... See more keywords
H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-020-20614-1
Abstract: Although it is well established that the Polycomb Group (PcG) complexes maintain gene repression through the incorporation of H2AK121ub and H3K27me3, little is known about the effect of these modifications on chromatin accessibility, which is… read more here.
Keywords: accessible chromatin; chromatin; regulation hotspots; chromatin accessibility ... See more keywords
2 The landscape of accessible chromatin in bovine oocytes and early embryos
Sign Up to like & getrecommendations! Published in 2020 at "Reproduction, Fertility and Development"
DOI: 10.1071/rdv32n2ab2
Abstract: Chromatin reorganization governs gene expression regulation during pre-implantation development. However, the global chromatin landscape and its dynamics in this period remain unexplored in bovine. In this study, we constructed a genome-wide map of accessible chromatin… read more here.
Keywords: accessible chromatin; chromatin; bovine; landscape ... See more keywords
Selection on accessible chromatin regions in Capsella grandiflora.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology and evolution"
DOI: 10.1093/molbev/msab270
Abstract: Accurate estimates of genome-wide rates and fitness effects of new mutations are essential for an improved understanding of molecular evolutionary processes. Although eukaryotic genomes generally contain a large non-coding fraction, functional non-coding regions and fitness… read more here.
Keywords: accessible chromatin; chromatin regions; selection; non coding ... See more keywords
Analysis of accessible chromatin landscape in the inner cell mass and trophectoderm of human blastocysts.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular human reproduction"
DOI: 10.1093/molehr/gaaa048
Abstract: Early embryonic development is characterized by drastic changes in chromatin structure that affects the accessibility of the chromatin. In human, the chromosome reorganization and its involvement in the first linage segregation are poorly characterized due… read more here.
Keywords: accessible chromatin; chromatin; cell mass; landscape ... See more keywords
The accessible chromatin landscape of the murine hippocampus at single-cell resolution.
Sign Up to like & getrecommendations! Published in 2019 at "Genome research"
DOI: 10.1101/gr.243725.118
Abstract: Here we present a comprehensive map of the accessible chromatin landscape of the mouse hippocampus at single-cell resolution. Substantial advances of this work include the optimization of a single-cell combinatorial indexing assay for transposase accessible… read more here.
Keywords: single cell; accessible chromatin; landscape; cell ... See more keywords
Characterization of Accessible Chromatin Regions in Cattle Rumen Epithelial Tissue during Weaning
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13030535
Abstract: Weaning in ruminants is characterized by the transition from a milk-based diet to a solid diet, which drives a critical gastrointestinal tract transformation. Understanding the regulatory control of this transformation during weaning can help to… read more here.
Keywords: rumen development; accessible chromatin; cattle rumen; rumen epithelial ... See more keywords
The Landscape of Accessible Chromatin during Yak Adipocyte Differentiation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179960
Abstract: Although significant advancement has been made in the study of adipogenesis, knowledge about how chromatin accessibility regulates yak adipogenesis is lacking. We here described genome-wide dynamic chromatin accessibility in preadipocytes and adipocytes by using the… read more here.
Keywords: adipogenesis; chromatin yak; accessible chromatin; chromatin ... See more keywords