Accessing pyrrolones and pyridinones: controlling 5-exo and 6-endo ring closures in heterocyclic alkynylamides
Sign Up to like & getrecommendations! Published in 2017 at "Canadian Journal of Chemistry"
DOI: 10.1139/cjc-2016-0524
Abstract: Competitive 5-exo and 6-endo anionic intramolecular cyclization reactions in heterocyclic alkynylamides were explored via experimental and computational analysis. The 5-exo-dig cyclization pathway is usually disfavoured in heterocyclic systems, and 6-endo products are often both the… read more here.
Keywords: dig; endo; exo endo; accessing pyrrolones ... See more keywords