Temporal changes in the accessory protein mutations of SARS‐CoV‐2 variants and their predicted structural and functional effects
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27964
Abstract: Emerging variants enable the continuous spread of SARS‐CoV‐2 in humans. The factors contributing to behavioral differences in variants remain elusive despite associations with several Spike protein mutations. Exploring accessory proteins may provide a wider understanding… read more here.
Keywords: functional effects; protein mutations; accessory protein; structural functional ... See more keywords
The importance of accessory protein variants in the pathogenicity of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2022 at "Archives of Biochemistry and Biophysics"
DOI: 10.1016/j.abb.2022.109124
Abstract: The coronavirus disease 2019 (COVID-19) is caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS- CoV-2) with an estimated fatality rate of less than 1%. The SARS-CoV-2 accessory proteins ORF3a, ORF6, ORF7a, ORF7b, ORF8, and… read more here.
Keywords: pathogenicity sars; sars cov; importance accessory; accessory proteins ... See more keywords
Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS.
Sign Up to like & getrecommendations! Published in 2022 at "Nature neuroscience"
DOI: 10.1038/s41593-022-01040-6
Abstract: The noncoding genome is substantially larger than the protein-coding genome but has been largely unexplored by genetic association studies. Here, we performed region-based rare variant association analysis of >25,000 variants in untranslated regions of 6,139… read more here.
Keywords: receptor accessory; interleukin receptor; protect als; protein ... See more keywords
The roles of interleukin-1 receptor accessory protein in certain inflammatory conditions.
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13462
Abstract: Interleukin-1 receptor accessory protein (IL-1RAcP) is a member of the immunoglobulin superfamily proteins consisting of soluble and membranous isoforms. IL-1RAcP plays an essential role in the signaling of the IL-1 family cytokines such as IL-1,… read more here.
Keywords: receptor accessory; interleukin receptor; accessory protein;
The GPCR accessory protein MRAP2 regulates both biased signaling and constitutive activity of the ghrelin receptor GHSR1a
Sign Up to like & getrecommendations! Published in 2020 at "Science Signaling"
DOI: 10.1126/scisignal.aax4569
Abstract: An accessory protein suppresses β-arrestin–dependent signaling and constitutive activity of the ghrelin receptor. Skewing signaling with an accessory protein Ghrelin is a peptide that is secreted by the stomach during fasting to promote food intake.… read more here.
Keywords: protein; accessory protein; constitutive activity; ghsr1a ... See more keywords
Intracellular localization of GGA accessory protein p56 in cell lines and central nervous system neurons.
Sign Up to like & getrecommendations! Published in 2018 at "Biomedical research"
DOI: 10.2220/biomedres.39.179
Abstract: Adaptor protein complex-1 (AP-1) and Golgi associated, γ-adaptin ear containing, Arf binding proteins (GGAs) are clathrin adaptors that regulate membrane trafficking between the trans-Golgi network (TGN) and endosomes. p56 is a clathrin adaptor accessory protein… read more here.
Keywords: protein; accessory protein; cell lines; central nervous ... See more keywords
Recombinant Family 1 Carbohydrate-Binding Modules Derived From Fungal Cellulase Enhance Enzymatic Degradation of Lignocellulose as Novel Effective Accessory Protein
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.876466
Abstract: Fungal cellulases usually contain a family 1 carbohydrate-binding module (CBM1), and its role was considered to recognize the substrate specifically. This study testified that the CBM1s derived from cellobiohydrolase I of Trichoderma reesei, Penicillium oxalicum,… read more here.
Keywords: effective accessory; family carbohydrate; carbohydrate binding; cellulase ... See more keywords
Human Melanocortin-2 Receptor: Identifying a Role for Residues in the TM4, EC2, and TM5 Domains in Activation and Trafficking as a Result of Co-Expression with the Accessory Protein, Mrap1 in Chinese Hamster Ovary Cells
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101422
Abstract: Human melanocortin-2 receptor (hMC2R) co-expressed with the accessory protein mouse (m)MRAP1 in Chinese Hamster Ovary (CHO) cells has been used as a model system to investigate the activation and trafficking of hMC2R. A previous study… read more here.
Keywords: human melanocortin; hmc2r; melanocortin receptor; receptor ... See more keywords
Functional characterization and proteomic analysis of porcine deltacoronavirus accessory protein NS7.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of microbiology and biotechnology"
DOI: 10.4014/jmb.1908.08013
Abstract: Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus which causes diarrhea in neonatal piglets. Like other coronaviruses, PDCoV encodes at least three accessory or species-specific proteins; however, the biological roles of these proteins in… read more here.
Keywords: protein; accessory protein; porcine; proteomic analysis ... See more keywords