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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27123807
Abstract: Compromised activity is a common impediment for biologics requiring endosome trafficking into target cells. In cancer cells, antibody-drug conjugates (ADCs) are trapped in endosomes or subsequently pumped extracellularly, leading to a reduction in intracellular accumulation.…
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Keywords:
novel conjugable;
immunotherapy;
onco immunotherapy;
accum technology ... See more keywords