Association of Longitudinal β-Amyloid Accumulation Determined by Positron Emission Tomography With Clinical and Cognitive Decline in Adults With Probable Lewy Body Dementia
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2019.16439
Abstract: Key Points Question What is the trajectory of β-amyloid accumulation over time, and how is it associated with clinical and cognitive decline among patients with probable dementia with Lewy bodies? Findings This cohort study of… read more here.
Keywords: lewy bodies; dementia lewy; accumulation; amyloid accumulation ... See more keywords
Association of Excessive Daytime Sleepiness With Longitudinal &bgr;-Amyloid Accumulation in Elderly Persons Without Dementia
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2018.0049
Abstract: Importance Aging is associated with excessive daytime sleepiness (EDS), which has been linked to cognitive decline in the elderly. However, whether EDS is associated with the pathologic processes of Alzheimer disease remains unclear. Objective To… read more here.
Keywords: accumulation; bgr; excessive daytime; cingulate ... See more keywords
Association of Initial β-Amyloid Levels With Subsequent Flortaucipir Positron Emission Tomography Changes in Persons Without Cognitive Impairment.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2020.3921
Abstract: Importance Tau accumulation in Alzheimer disease (AD) is closely associated with cognitive impairment. Quantitating tau accumulation by positron emission tomography (PET) will be a useful outcome measure for future clinical trials in the AD spectrum.… read more here.
Keywords: accumulation; pet; tau accumulation; suvr units ... See more keywords
Downregulation of adipose triglyceride lipase by EB viral‐encoded LMP2A links lipid accumulation to increased migration in nasopharyngeal carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12824
Abstract: Epstein–Barr virus (EBV)‐associated nasopharyngeal carcinoma (NPC) is one of the most common human cancers in South‐East Asia exhibiting typical features of lipid accumulation. EBV‐encoded latent membrane protein 2A (LMP2A) is expressed in most NPCs enhancing… read more here.
Keywords: accumulation; lipid accumulation; migration; downregulation ... See more keywords
Carbonic anhydrase 3 increases during liver adipogenesis even in pre‐obesity, and its inhibitors reduce liver adipose accumulation
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13376
Abstract: The abnormal lipid metabolism in the liver that occurs after high caloric intake is the main cause of nonalcoholic fatty liver disease (NAFLD). Differences between samples from healthy livers and livers from individuals with NAFLD… read more here.
Keywords: carbonic anhydrase; fat accumulation; accumulation; expression ... See more keywords
Novel approach to semi‐quantification of tracer accumulation in dopamine transporter scan
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.13626
Abstract: Abstract Purpose Accurate tracer accumulation evaluation is difficult owing to the partial volume effect (PVE). We proposed a novel semi‐quantitative approach for measuring the accumulation amount by examining the approximate image. Using a striatal phantom,… read more here.
Keywords: tracer; region; accumulation amounts; accumulation ... See more keywords
Quantifying regional α ‐synuclein, amyloid β, and tau accumulation in lewy body dementia
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51482
Abstract: Parkinson disease (PD) is defined by the accumulation of misfolded α‐synuclein (α‐syn) in Lewy bodies and Lewy neurites. It affects multiple cortical and subcortical neuronal populations. The majority of people with PD develop dementia, which… read more here.
Keywords: body dementia; tau accumulation; accumulation; amyloid tau ... See more keywords
Effective Transplantation of 2D and 3D Cultured Hepatocyte Spheroids Confirmed by Quantum Dot Imaging
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Biosystems"
DOI: 10.1002/adbi.201800137
Abstract: Liver transplantation is the most effective treatment for patients with end‐stage liver diseases, but hepatocyte transplantation using spheroids is expected to become an alternative strategy owing to the limited number of liver donors. However, the… read more here.
Keywords: effective transplantation; accumulation; cultured hepatocyte; transplantation cultured ... See more keywords
Zwitterionic Polymer Coating of Sulfur Dioxide-Releasing Nanosystem Augments Tumor Accumulation and Treatment Efficacy.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901582
Abstract: Multiple drug resistance (MDR) exhibited by cancer cells and low intratumor accumulation of chemotherapeutics are the main obstacles in cancer chemotherapy. Herein, the preparation of a redox-responsive sulfur dioxide (SO2 )-releasing nanosystem, with high SO2… read more here.
Keywords: accumulation; releasing nanosystem; tumor accumulation; sulfur dioxide ... See more keywords
Enhanced Tumor Accumulation of Multimodal Magneto‐Plasmonic Nanoparticles via an Implanted Micromagnet‐Assisted Delivery Strategy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201585
Abstract: One of the major shortcomings of nano carriers‐assisted cancer therapeutic strategies continues to be the inadequate tumor penetration and retention of systemically administered nanoformulations and its off‐target toxicity. Stromal parameters‐related heterogeneity in enhanced permeability and… read more here.
Keywords: micromagnet; accumulation; plasmonic nanoparticles; magneto plasmonic ... See more keywords
Characterization and Quantification of Depletion and Accumulation Layers in Solid-State Li+ -Conducting Electrolytes Using In Situ Spectroscopic Ellipsometry.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202100585
Abstract: The future of mobility depends on the development of next-generation battery technologies, such as all-solid-state batteries. As the ionic conductivity of solid Li+ -conductors can, in some cases, approach that of liquid electrolytes, a significant… read more here.
Keywords: solid state; state; accumulation; spectroscopic ellipsometry ... See more keywords