The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death
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DOI: 10.1186/s12974-018-1134-4
Abstract: BackgroundCurrently, several amyloid beta (Aβ) antibodies, including the protofibril selective antibody BAN2401, are in clinical trials. The murine version of BAN2401, mAb158, has previously been shown to lower the levels of pathogenic Aβ and prevent… read more here.
Keywords: selective antibody; accumulation astrocytes; protofibril selective; cell death ... See more keywords