SIRT3 overexpression and epigenetic silencing of catalase regulate ROS accumulation in CLL cells activating AXL signaling axis
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DOI: 10.1038/s41408-021-00484-6
Abstract: Mitochondrial metabolism is the key source for abundant ROS in chronic lymphocytic leukemia (CLL) cells. Here, we detected significantly lower superoxide anion (O2−) levels with increased accumulation of hydrogen peroxide (H2O2) in CLL cells vs.… read more here.
Keywords: cll; ros accumulation; accumulation cll; sirt3 overexpression ... See more keywords