Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes
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DOI: 10.7150/thno.45003
Abstract: Disturbed renal lipid metabolism, especially cholesterol dysregulation plays a crucial role in the pathogenesis of chronic kidney disease (CKD). We recently reported that angiotensin (Ang) II could induce cholesterol accumulation and injury in podocytes. However,… read more here.
Keywords: accumulation injury; sirt6; cholesterol accumulation; cholesterol ... See more keywords