Accurate determination of drug-to-antibody ratio of interchain cysteine-linked antibody–drug conjugates by LC-HRMS
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-02280-5
Abstract: Accurate determination of the drug-to-antibody ratio (DAR) of interchain cysteine-linked antibody–drug conjugates (ADCs) is challenging. High-resolution mass spectrometry (HRMS) analysis of the ADCs at the intact or subunit level provides a feasible way to measure… read more here.
Keywords: dar; cysteine linked; accurate determination; drug ... See more keywords
Biotechnology-enhanced immunoassay for accurate determination of HT-2 toxin in edible insect samples
Sign Up to like & getrecommendations! Published in 2025 at "Mikrochimica Acta"
DOI: 10.1007/s00604-025-07146-5
Abstract: Consumption of edible insects is common in non-Western countries of Africa, Asia, Oceania, and Latin America. However, their consumption has significantly increased in Europe in recent years thanks to their remarkable nutritional properties. Edible insects… read more here.
Keywords: biotechnology enhanced; accurate determination; determination toxin; immunoassay accurate ... See more keywords
Rapid and accurate determination of gold in geological materials by an improved ICP-MS method
Sign Up to like & getrecommendations! Published in 2017 at "Microchemical Journal"
DOI: 10.1016/j.microc.2017.09.014
Abstract: Abstract Accurate determination of gold (Au) in geological materials by inductively coupled plasma mass spectrometry (ICP-MS) is suffered to significant Ta and Hf oxide interferences. An improved method based on Ar aerosol dilution ICP-MS after… read more here.
Keywords: gold geological; determination gold; geological materials; determination ... See more keywords
Accurate Determination and Characterization of Gold Nanoparticles Based on Single Particle-Inductively Coupled Plasma-Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Journal of Analytical Chemistry"
DOI: 10.1016/s1872-2040(20)60032-9
Abstract: Abstract An accurate determination method for gold nanoparticles (AuNPs) number concentration and size was developed based on single particle-inductively coupled plasma-mass spectrometry (SP-ICP-MS). Influencing parameters such as different calculation methods of transport efficiency, dwell time,… read more here.
Keywords: gold nanoparticles; accurate determination; particle; single particle ... See more keywords
New Coarse Variables for the Accurate Determination of Standard Binding Free Energies.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.7b00791
Abstract: To improve sampling of the configurational entropy change upon protein-ligand binding, we have introduced a new set of coarse variables describing the relative orientation and position of the ligand via a global macromolecular orientational procedure,… read more here.
Keywords: new coarse; standard binding; variables accurate; accurate determination ... See more keywords
Accurate Determination of Cavitand Binding Free Energies via Unrestrained Advanced Sampling.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.9b00348
Abstract: Calculation of binding free energies, which characterize the stability and specificity of molecular interactions (e.g., drug formulations), has been established as an important application of modern computational chemistry. Though several methodologies currently exist within the… read more here.
Keywords: unrestrained advanced; advanced sampling; free energies; calculation ... See more keywords
Chiral sulfoxides: advances in asymmetric synthesis and problems with the accurate determination of the stereochemical outcome.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Society reviews"
DOI: 10.1039/c6cs00703a
Abstract: Chiral sulfoxides are in extremely high demand in nearly every sector of the chemical industry concerned with the design and development of new synthetic reagents, drugs, and functional materials. The primary objective of this review… read more here.
Keywords: chiral sulfoxides; determination stereochemical; chemistry; accurate determination ... See more keywords
Accurate determination of stable silver isotopes in zinc-rich samples by effective separation of silver and zinc
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Analytical Atomic Spectrometry"
DOI: 10.1039/d4ja00125g
Abstract: Silver isotopes have been extensively used in environment, archaeology, and economic geology. Nevertheless, accurate analyses of Ag isotope ratios face challenges caused by presence of matrix elements (e.g. Zn, Cu,... read more here.
Keywords: accurate determination; isotopes zinc; silver; stable silver ... See more keywords
Accurate determination of ultra-trace rare earth elements by LA-ICP-MS/MS and its application to cassiterite for effective elimination of Gd and Tb false positive anomalies
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Analytical Atomic Spectrometry"
DOI: 10.1039/d4ja00271g
Abstract: Rare earth elements (REE) are widely used as important geochemical tracers in earth and planetary sciences. Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) techniques have been routinely used for... read more here.
Keywords: ultra trace; accurate determination; determination ultra; rare earth ... See more keywords
Accurate determination of low-field mobility in tri-gate junctionless transistors
Sign Up to like & getrecommendations! Published in 2020 at "Semiconductor Science and Technology"
DOI: 10.1088/1361-6641/ab607d
Abstract: The simple device structure of junctionless transistors (JLTs), which lack PN junctions and involve bulk-conduction-based operation, is an attractive component for the future fulfilment of Moore's law. However, the unique bulk conduction mechanism of JLTs… read more here.
Keywords: low field; tri gate; accurate determination; field mobility ... See more keywords
Accurate determination of the shapes of granular charge distributions.
Sign Up to like & getrecommendations! Published in 2023 at "Physical review. E"
DOI: 10.1103/physreve.107.034901
Abstract: Experiments have shown that charge distributions of granular materials are non-Gaussian, with broad tails that indicate many particles with high charge. This observation has consequences for the behavior of granular materials in many settings, and… read more here.
Keywords: charge distributions; accurate determination; charge; shapes granular ... See more keywords