Accurate determination of drug-to-antibody ratio of interchain cysteine-linked antibody–drug conjugates by LC-HRMS
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-02280-5
Abstract: Accurate determination of the drug-to-antibody ratio (DAR) of interchain cysteine-linked antibody–drug conjugates (ADCs) is challenging. High-resolution mass spectrometry (HRMS) analysis of the ADCs at the intact or subunit level provides a feasible way to measure… read more here.
Keywords: dar; cysteine linked; accurate determination; drug ... See more keywords
Rapid and accurate determination of gold in geological materials by an improved ICP-MS method
Sign Up to like & getrecommendations! Published in 2017 at "Microchemical Journal"
DOI: 10.1016/j.microc.2017.09.014
Abstract: Abstract Accurate determination of gold (Au) in geological materials by inductively coupled plasma mass spectrometry (ICP-MS) is suffered to significant Ta and Hf oxide interferences. An improved method based on Ar aerosol dilution ICP-MS after… read more here.
Keywords: gold geological; determination gold; geological materials; determination ... See more keywords
Accurate Determination and Characterization of Gold Nanoparticles Based on Single Particle-Inductively Coupled Plasma-Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Journal of Analytical Chemistry"
DOI: 10.1016/s1872-2040(20)60032-9
Abstract: Abstract An accurate determination method for gold nanoparticles (AuNPs) number concentration and size was developed based on single particle-inductively coupled plasma-mass spectrometry (SP-ICP-MS). Influencing parameters such as different calculation methods of transport efficiency, dwell time,… read more here.
Keywords: gold nanoparticles; accurate determination; particle; single particle ... See more keywords
New Coarse Variables for the Accurate Determination of Standard Binding Free Energies.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.7b00791
Abstract: To improve sampling of the configurational entropy change upon protein-ligand binding, we have introduced a new set of coarse variables describing the relative orientation and position of the ligand via a global macromolecular orientational procedure,… read more here.
Keywords: new coarse; standard binding; variables accurate; accurate determination ... See more keywords
Accurate Determination of Cavitand Binding Free Energies via Unrestrained Advanced Sampling.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.9b00348
Abstract: Calculation of binding free energies, which characterize the stability and specificity of molecular interactions (e.g., drug formulations), has been established as an important application of modern computational chemistry. Though several methodologies currently exist within the… read more here.
Keywords: unrestrained advanced; advanced sampling; free energies; calculation ... See more keywords
Chiral sulfoxides: advances in asymmetric synthesis and problems with the accurate determination of the stereochemical outcome.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Society reviews"
DOI: 10.1039/c6cs00703a
Abstract: Chiral sulfoxides are in extremely high demand in nearly every sector of the chemical industry concerned with the design and development of new synthetic reagents, drugs, and functional materials. The primary objective of this review… read more here.
Keywords: chiral sulfoxides; determination stereochemical; chemistry; accurate determination ... See more keywords
Accurate determination of low-field mobility in tri-gate junctionless transistors
Sign Up to like & getrecommendations! Published in 2020 at "Semiconductor Science and Technology"
DOI: 10.1088/1361-6641/ab607d
Abstract: The simple device structure of junctionless transistors (JLTs), which lack PN junctions and involve bulk-conduction-based operation, is an attractive component for the future fulfilment of Moore's law. However, the unique bulk conduction mechanism of JLTs… read more here.
Keywords: low field; tri gate; accurate determination; field mobility ... See more keywords
Accurate determination of the shapes of granular charge distributions.
Sign Up to like & getrecommendations! Published in 2023 at "Physical review. E"
DOI: 10.1103/physreve.107.034901
Abstract: Experiments have shown that charge distributions of granular materials are non-Gaussian, with broad tails that indicate many particles with high charge. This observation has consequences for the behavior of granular materials in many settings, and… read more here.
Keywords: charge distributions; accurate determination; charge; shapes granular ... See more keywords
Accurate Determination of the Dynamical Polarizability of Dysprosium.
Sign Up to like & getrecommendations! Published in 2018 at "Physical review letters"
DOI: 10.1103/physrevlett.120.223001
Abstract: We report a measurement of the dynamical polarizability of dysprosium atoms in their electronic ground state at the optical wavelength of 1064 nm, which is of particular interest for laser trapping experiments. Our method is based… read more here.
Keywords: polarizability dysprosium; accurate determination; determination dynamical; dynamical polarizability ... See more keywords
Measurement System for Accurate Determination of Fast-Changing DC Currents Up To 900 A
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Transactions on Instrumentation and Measurement"
DOI: 10.1109/tim.2023.3277995
Abstract: Accurate measurement of fast-changing direct current (dc) is of great importance for high-power, high-resolution amplifiers generating fast-changing pulsed dc currents, for example, used in magnetic resonance imaging (MRI) systems. A setup and a comprehensive measurement… read more here.
Keywords: fast changing; accurate determination; determination fast; method ... See more keywords
Accurate Determination of Trace Cadmium in Soil Samples with Graphite Furnace Atomic Absorption Spectrometry Using Metal–Organic Frameworks as Matrix Modifiers
Sign Up to like & getrecommendations! Published in 2022 at "Applied Spectroscopy"
DOI: 10.1177/00037028221141709
Abstract: Cadmium (Cd) is a highly toxic heavy metal that is widely distributed in soils at low concentrations. Its volatilization loss occurs at an ashing temperature higher than 350 °C. Accordingly, the accurate determination of its… read more here.
Keywords: atomic absorption; graphite furnace; spectroscopy; accurate determination ... See more keywords