Long-term ACE inhibition in Alport syndrome: are the benefits worth the risks?
Sign Up to like & getrecommendations! Published in 2020 at "Kidney international"
DOI: 10.1016/j.kint.2020.01.030
Abstract: Gross et al. present results of the EARLY PRO-TECT trial, a randomized controlled trial of ramipril versus placebo in children with early-stage Alport syndrome. Although under-enrolled and not a positive trial in the traditional sense, EARLY… read more here.
Keywords: long term; ace inhibition; inhibition alport; alport syndrome ... See more keywords
ACE-inhibition induces a cardioprotective transcriptional response in the metabolic syndrome heart
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-34547-9
Abstract: Cardiovascular disease associated with metabolic syndrome has a high prevalence, but the mechanistic basis of metabolic cardiomyopathy remains poorly understood. We characterised the cardiac transcriptome in a murine metabolic syndrome (MetS) model (LDLR−/−; ob/ob, DKO)… read more here.
Keywords: ace; ace inhibition; metabolic syndrome; transcriptional response ... See more keywords
P0720CARVEDILOL AND NON-DIHYDROPYRIDINE CALCIUM CHANNELS BLOCKERS DELAY THE PROGRESSION OF CHRONIC KIDNEY DISEASE BEYOND ACE-INHIBITION IN KWAZULU-NATAL (SOUTH AFRICA)
Sign Up to like & getrecommendations! Published in 2020 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaa142.p0720
Abstract: Chronic kidney disease (CKD) is on the rise worldwide. It is associated with increased morbidity and mortality and places a huge burden on cost constrained health systems in developing countries such as South Africa. ACE… read more here.
Keywords: ace inhibition; inhibition; kidney disease; chronic kidney ... See more keywords