Rapid screening and identification of ACE inhibitors in snake venoms using at-line nanofractionation LC-MS
Sign Up to like & getrecommendations! Published in 2017 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-017-0531-3
Abstract: This study presents an analytical method for the screening of snake venoms for inhibitors of the angiotensin-converting enzyme (ACE) and a strategy for their rapid identification. The method is based on an at-line nanofractionation approach,… read more here.
Keywords: snake venoms; line nanofractionation; ace inhibitors; identification ... See more keywords
Should ACE inhibitors and ARBs be used in combination in children?
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Nephrology"
DOI: 10.1007/s00467-018-4046-8
Abstract: The renin-angiotensin-aldosterone system (RAAS) plays a pivotal role in a host of renal and cardiovascular functions. Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), drugs that disrupt RAAS function, are effective in treating hypertension… read more here.
Keywords: combination; arb therapy; acei arb; used combination ... See more keywords
The Combination of Beta-Blockers and ACE Inhibitors Across the Spectrum of Cardiovascular Diseases
Sign Up to like & getrecommendations! Published in 2021 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-021-07248-1
Abstract: Cardiovascular disease is the leading cause of mortality worldwide, affecting a wide range of patients at different stages across the cardiovascular continuum. Hypertension is one of the earliest risk factors in this continuum and can… read more here.
Keywords: single pill; beta blockers; ace inhibitors; cardiovascular ... See more keywords
COVID-19: A Concern for Cardiovascular Disease Patients
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DOI: 10.1007/s12012-020-09596-0
Abstract: Coronavirus disease 2019 (COVID-19) is declared as a pandemic that has spread worldwide, affecting 205 countries. The disease affected 1, 40, 43, 176 individuals and caused 5, 97, 583 deaths around the globe. The organism… read more here.
Keywords: covid concern; disease patients; disease; ace inhibitors ... See more keywords
Potent ACE inhibitors from 5-hydroxy indanone derivatives.
Sign Up to like & getrecommendations! Published in 2018 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.02.022
Abstract: A novel triazole derivatives(±)-2-(hydroxymethyl)-7,8-dihydro-1H-indeno[5,4-b]furan-6(2H)-one (12a-j) were designed and synthesized by the reaction between racemic azide and terminal acetylenes under click chemistry reaction conditions followed by biological evaluation as angiotensin converting enzyme (ACE) inhibitors. β-Amino alcohol… read more here.
Keywords: ic50; chemistry; ace inhibitors; hydroxy indanone ... See more keywords
Inpatient Omission of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers Is Associated With Morbidity and Mortality in Coronavirus Disease 2019
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Therapeutics"
DOI: 10.1016/j.clinthera.2021.02.004
Abstract: Purpose Due to the affinity of severe acute respiratory syndrome coronavirus 2 for the human angiotensin-converting enzyme 2 (ACE2) receptor, use of ACE inhibitors and angiotensin receptor blockers (ARBs) has been a major concern for… read more here.
Keywords: coronavirus; morbidity mortality; ace inhibitors; receptor ... See more keywords
Association of ACE inhibitors and angiotensin type II blockers with ACE2 overexpression in COVID-19 comorbidities: A pathway-based analytical study
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2021.173899
Abstract: Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) outbreak is a major public health concern, which has accounted for >1.7 million deaths across the world. A surge in the case fatality ratio as compared with… read more here.
Keywords: association ace; association; ace inhibitors; sars cov ... See more keywords
Angiotensin-Converting Enzyme Inhibitors in Hypertension: To Use or Not to Use?
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DOI: 10.1016/j.jacc.2018.01.058
Abstract: Most guidelines for the management of patients with cardiovascular disease recommend angiotensin-converting enzyme (ACE) inhibitors as first-choice therapy, whereas angiotensin receptor blockers (ARBs) are merely considered an alternative for ACE inhibitor-intolerant patients. The aim of… read more here.
Keywords: hypertension; angiotensin converting; use; ace inhibitors ... See more keywords
Trimethylamine N-oxide and ACE inhibitors: fighting a new enemy with an established weapon?
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DOI: 10.1080/1354750x.2018.1458154
Abstract: Choline and choline-metabolites such as trimethylamine N-oxide (TMAO) have been investigated as cardiac biomarkers for many years (Danne et al. 2003, Danne and M€ ockel 2010). Hazen et al. (2011) demonstrated that three major metabolites… read more here.
Keywords: choline; tmao; disease; ace inhibitors ... See more keywords
Benefit and risk evaluation of quinapril hydrochloride
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DOI: 10.1080/14740338.2023.2203481
Abstract: ABSTRACT Introduction Angiotensin-converting enzyme (ACE) inhibitors are a mainstay of antihypertensive therapy. Quinapril hydrochloride, a less commonly used, and less-studied ACE inhibitor has been approved for its primary use in hypertension. Studies also indicate its… read more here.
Keywords: benefit risk; quinapril hydrochloride; quinapril; ace ... See more keywords
BISOPROLOL BETTER THAN ATENOLOL AS ADD ON THERAPY TO ACE INHIBITORS IN BLOOD PRESSURE CONTROL
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DOI: 10.1097/01.hjh.0000539074.54110.f7
Abstract: Objective: ACE-inhibitors (ACEi) are a first choice treatment in arterial hypertension as reported in European and American guidelines. However, in order to reach the optimal target blood pressure (BP), frequently adding another drug is needed.… read more here.
Keywords: blood pressure; group; target; ace inhibitors ... See more keywords