Stimulation of ACE2/ANG(1–7)/Mas Axis by Diminazene Ameliorates Alzheimer’s Disease in the D-Galactose-Ovariectomized Rat Model: Role of PI3K/Akt Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-0966-3
Abstract: Overactivation of angiotensin-converting enzyme/angiotensin 2/angiotensin receptor-1 (ACE/Ang2/AT1) axis provokes amyloid-β-induced apoptosis and neurodegeneration in Alzheimer’s disease (AD). Moreover, activation of AT1 impairs the survival pathway phosphoinositide 3-kinase/protein kinase B (PI3K/Akt). Interestingly, the coupling between ACE2/Ang(1–7)/Mas… read more here.
Keywords: ang mas; ace2 ang; ace2; pi3k akt ... See more keywords
N-Acetyl-Seryl-Asparyl-Lysyl-Proline interaction with ACE2-Ang (1-7)-Mas axis attenuates pulmonary fibrosis in silicotic rats.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental physiology"
DOI: 10.1113/ep087515
Abstract: NEW FINDINGS What is the central question of this study? To explore the effects of Ac-SDKP on ACE2/Ang (1-7)/Mas axis in occurrence and progress of silicosis. What is the main finding and its importance? Ac-SDKP… read more here.
Keywords: silicosis; ace2 ang; ang mas; ang ... See more keywords
Chrysin Attenuates Fructose-Induced Nonalcoholic Fatty Liver in Rats via Antioxidant and Anti-Inflammatory Effects: The Role of Angiotensin-Converting Enzyme 2/Angiotensin (1-7)/Mas Receptor Axis
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/9479456
Abstract: Aim Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome, and if untreated, it may propagate into end-stage liver disease. The classical arm of the renin-angiotensin system (RAS) has a fundamental role… read more here.
Keywords: nonalcoholic fatty; converting enzyme; fatty liver; chrysin ... See more keywords
The function of the ACE2/Ang(1-7)/Mas receptor axis of the renin-angiotensin system in myocardial ischemia reperfusion injury.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202203_28330
Abstract: OBJECTIVE Angiotensin-converting enzyme 2(ACE2) is a critical element of the renin-angiotensin system (RAS), which can convert angiotensin (Ang)II to Ang(1-7), followed by binding Mas receptor (MasR) and subsequently produces cardioprotective effects through various signal transduction… read more here.
Keywords: angiotensin; ang; mas receptor; axis ... See more keywords
The protective effect of xanthenone against LPS-induced COVID-19 acute respiratory distress syndrome (ARDS) by modulating the ACE2/Ang-1-7 signaling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202207_29320
Abstract: OBJECTIVE: Acute respiratory distress syndrome (ARDS) is an inflammatory lung disease that has a high rate of morbidity and mortality. It's an acute diffusive lung injury caused by the release of pro-inflammatory cytokines into the… read more here.
Keywords: respiratory distress; distress syndrome; ace2; acute respiratory ... See more keywords
Role of the ACE2/Ang-(1-7)/Mas axis in glucose metabolism.
Sign Up to like & getrecommendations! Published in 2021 at "Reviews in cardiovascular medicine"
DOI: 10.31083/j.rcm2203083
Abstract: The renin-angiotensin system (RAS) helps to regulate cardiovascular function, the maintenance of electrolyte and fluid balance, and blood pressure. The RAS contains two axes; the angiotensin-converting enzyme/angiotensin II/Ang II type 1 receptors (ACE/Ang II/AT1) classic… read more here.
Keywords: ang mas; axis; glucose metabolism; ace2 ang ... See more keywords