Angiotensin-converting enzymes (ACE, ACE2) gene variants and COVID-19 outcome
Sign Up to like & getrecommendations! Published in 2020 at "Gene"
DOI: 10.1016/j.gene.2020.145102
Abstract: The Angiotensin system is implicated in the pathogenesis of COVID-19. First, ACE2 is the cellular receptor for SARS-CoV-2, and expression of the ACE2 gene could regulate the individuaĺs susceptibility to infection. In addition, the balance… read more here.
Keywords: outcome; covid; hypertension; gene ... See more keywords
SARS-COV-2 RECEPTOR ACE2 GENE is associated with hypertension and SEVERity of COVID 19: interaction with sex, obesity and SMOKING
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hypertension"
DOI: 10.1093/ajh/hpaa223
Abstract: Abstract Background ACE2 has been identified as the entry receptor for coronaviruses into human cells, including SARS-COV-2 that causes COVID-19. Since hypertension is a leading comorbidity in non-survivors of COVID-19, we tested for association between… read more here.
Keywords: ace2 gene; interaction; hypertension; smoking ... See more keywords
A3216 Relationship between genetic variants of ACE2 gene and circulating levels of ACE2 and its metabolites
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000547992.85595.35
Abstract: Objectives: Because heritability had remarkable effects on circulating ACE2, we designed this study to shed light on whether circulating levels of ACE2, angiotensin- (1- 7) and angiotensin- (1- 9) were linked to single nucleotide polymorphisms… read more here.
Keywords: levels ace2; angiotensin levels; circulating angiotensin; ace2 gene ... See more keywords
Relationship between genetic variants of ACE2 gene and circulating levels of ACE2 and its metabolites
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.12625
Abstract: Angiotensin‐converting enzyme 2 (ACE2) plays an important role in the development of essential hypertension (EH). Genetic factors remarkably influence circulating ACE2 level. read more here.
Keywords: relationship genetic; genetic variants; gene circulating; variants ace2 ... See more keywords
Role of ACE2 Gene Expression in Renin Angiotensin System and Its Importance in Covid-19: In Silico Approach
Sign Up to like & getrecommendations! Published in 2020 at "Brazilian Archives of Biology and Technology"
DOI: 10.1590/1678-4324-2020200304
Abstract: Abstract We aimed to analyze the expression profile of ACE2 and similar genes with ACE2, predict the number of variations in ACE2, detect the suspected SNPs on ACE2 gene, and perform the pathway analysis of… read more here.
Keywords: renin angiotensin; expression; angiotensin system; gene ... See more keywords
Association of ACE2 gene functional variants with gestational diabetes mellitus risk in a southern Chinese population
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.1052906
Abstract: Objective To explore the relationship between angiotensin-converting enzyme 2 (ACE2) genetic variants and gestational diabetes mellitus (GDM) in a southern Chinese population. Methods Potential functional variants (rs2106809, rs6632677, and rs2074192) of ACE2 were selected and… read more here.
Keywords: gdm; interaction; ace2 gene; risk ... See more keywords
ACE and ACE2 Gene Variants Are Associated With Severe Outcomes of COVID-19 in Men
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.812940
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current coronavirus disease 2019 (COVID-19) pandemic, affecting more than 219 countries and causing the death of more than 5 million people worldwide. The genetic… read more here.
Keywords: variants associated; ace ace2; ace2 gene; outcomes covid ... See more keywords
Analysis of ACE2 Gene-Encoded Proteins Across Mammalian Species
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2020.00457
Abstract: Human beings are currently experiencing a serious public health event. Novel coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), has infected about 3 million people worldwide and killed more… read more here.
Keywords: novel coronavirus; analysis; ace2 gene; mammalian species ... See more keywords
Association of ACE2 Gene Variants with the Severity of COVID-19 Disease—A Prospective Observational Study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph191912622
Abstract: The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2), has triggered an enormous scientific response. Many studies have focused on understanding the entry of the SARS-CoV-2 virus into the host cell.… read more here.
Keywords: covid disease; disease; ace2 gene; ace2 ... See more keywords