Design of novel disturbing peptides against ACE2 SARS-CoV-2 spike-binding region by computational approaches
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.996005
Abstract: The SARS-CoV-2, the virus which is responsible for COVID-19 disease, employs its spike protein to recognize its receptor, angiotensin-converting enzyme 2 (ACE2), and subsequently enters the host cell. In this process, the receptor-binding domain (RBD)… read more here.
Keywords: ace2 sars; novel disturbing; peptides ace2; design novel ... See more keywords
Characterization of Critical Determinants of ACE2–SARS CoV-2 RBD Interaction
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22052268
Abstract: Despite sequence similarity to SARS-CoV-1, SARS-CoV-2 has demonstrated greater widespread virulence and unique challenges to researchers aiming to study its pathogenicity in humans. The interaction of the viral receptor binding domain (RBD) with its main… read more here.
Keywords: cov rbd; characterization critical; critical determinants; determinants ace2 ... See more keywords