The renin‐angiotensin system in COVID‐19: Why ACE2 targeting by coronaviruses produces higher mortality in elderly hypertensive patients?
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DOI: 10.1002/bies.202000112
Abstract: This renin‐angiotensin system (RAS) interpretation is focused on differences in tissue dependence on RAS and on the topological hierarchy that allows mediators to act only on downstream tissues. read more here.
Keywords: ace2 targeting; renin angiotensin; system covid; covid ace2 ... See more keywords
A broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants
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DOI: 10.1038/s41467-021-25331-x
Abstract: The successive emergences and accelerating spread of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages and evolved resistance to some ongoing clinical therapeutics increase the risks associated with the coronavirus disease 2019 (COVID-19) pandemic.… read more here.
Keywords: ace2 targeting; humanized ace2; antibody; neutralizing humanized ... See more keywords
Pharmacotherapy Based on ACE2 Targeting and COVID-19 Infection
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DOI: 10.3390/ijms23126644
Abstract: The new SARS-CoV-2 coronavirus is responsible for the COVID-19 pandemic. A massive vaccination campaign, which is still ongoing, has averted most serious consequences worldwide; however, lines of research are continuing to identify the best drug… read more here.
Keywords: covid infection; ace2 targeting; infection; pharmacotherapy based ... See more keywords