Liquid Chromatographic Chiral Separation of Acenocoumarol and Its Hemiketal Form.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmx061
Abstract: Acenocoumarol, an anticoagulant drug, was separated successfully using polysaccharide-based chiral stationary phases columns namely Cellulose Chiralpak® IB and Chiralcel® OD, using various normal mobile phases by high-performance liquid chromatography. However, the appearance of four well… read more here.
Keywords: liquid chromatographic; hemiketal form; acenocoumarol; chromatographic chiral ... See more keywords
Development of a Fluorescent Microfluidic Device Based on Antibody Microarray Read-Out for Therapeutic Drug Monitoring of Acenocoumarol
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.848501
Abstract: The development of a proof-of-concept point-of-care (PoC) device for the determination of oral anticoagulants determination is presented. Acenocoumarol (ACL) is prescribed to prevent certain cardiovascular diseases related to the prevention of deep vein thrombosis, pulmonary… read more here.
Keywords: development fluorescent; development; acenocoumarol; microarray ... See more keywords
A Pharmacogenetically Guided Acenocoumarol Dosing Algorithm for Chilean Patients: A Discovery Cohort Study
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00325
Abstract: Background Vitamin K antagonists (VKA) are used as prophylaxis for thromboembolic events in patients with cardiovascular diseases. The most common VKA are warfarin and acenocoumarol. These drugs have a narrow therapeutic margin and high inter-individual… read more here.
Keywords: cyp2c9; discovery cohort; acenocoumarol; variability ... See more keywords
Acenocoumarol Exerts Anti-Inflammatory Activity via the Suppression of NF-κB and MAPK Pathways in RAW 264.7 Cells
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28052075
Abstract: The repurposing of already-approved drugs has emerged as an alternative strategy to rapidly identify effective, safe, and conveniently available new therapeutic indications against human diseases. The current study aimed to assess the repurposing of the… read more here.
Keywords: acenocoumarol; 264 cells; anti inflammatory; raw 264 ... See more keywords