Acetaldehyde Dehydrogenase 2(ALDH2) in Atherosclerosis: Beyond Detoxification of Reactive Aldehydes
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.10.191
Abstract: Previous studies have linked human polymorphisms of ALDH2 to cardiovascular diseases but the underlying mechanisms remain elusive. Here we investigated the role of ALDH2 in atherosclerosis using a murine model of low density lipoprotein receptor… read more here.
Keywords: acetaldehyde dehydrogenase; aldh2 atherosclerosis; atherosclerosis; detoxification reactive ... See more keywords
Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver
Sign Up to like & getrecommendations! Published in 2021 at "Redox Biology"
DOI: 10.1016/j.redox.2021.101919
Abstract: HMG-CoA reductase (HMGCR) is the rate-limiting enzyme in cholesterol biosynthesis and the target for cholesterol-lowering therapy. Acetaldehyde dehydrogenase 2 (ALDH2) is primarily responsible for detoxifying ethanol-derived acetaldehyde and endogenous lipid aldehydes derived from lipid peroxidation.… read more here.
Keywords: acetaldehyde dehydrogenase; hmg coa; cholesterol synthesis; cholesterol ... See more keywords
Introduction of bifunctional alcohol/acetaldehyde dehydrogenase gene (adhE) in Fructobacillus fructosus settled its fructophilic characteristics.
Sign Up to like & getrecommendations! Published in 2019 at "Research in microbiology"
DOI: 10.1016/j.resmic.2018.09.004
Abstract: Fructophilic lactic acid bacteria (FLAB) are unique in the sense that they prefer D-fructose over D-glucose as main carbon source. If D-glucose is metabolised, electron acceptors are required and significant levels of acetate are produced.… read more here.
Keywords: acetaldehyde dehydrogenase; alcohol acetaldehyde; fructophilic characteristics; strain ... See more keywords
Zymomonas mobilis ZM4 Utilizes an NADP+-Dependent Acetaldehyde Dehydrogenase To Produce Acetate
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bacteriology"
DOI: 10.1128/jb.00563-21
Abstract: Biofuel production from nonfood crops is an important strategy for reducing carbon emissions from the transportation industry, but it has not yet become commercially viable. An important avenue to improve biofuel production is to enhance… read more here.
Keywords: biofuel production; production; acetaldehyde dehydrogenase; acetate ... See more keywords
Optimal Secretory Expression of Acetaldehyde Dehydrogenase from Issatchenkia terricola in Bacillus subtilis through a Combined Strategy
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27030747
Abstract: Acetaldehyde dehydrogenases are potential enzyme preparations that can be used to detoxify acetaldehyde and other exogenous aldehydes from pharmaceuticals, food, and biofuel production. In this study, we enhanced the expression of acetaldehyde dehydrogenase sourced from… read more here.
Keywords: bacillus subtilis; acetaldehyde dehydrogenase; expression acetaldehyde; istaldh ... See more keywords