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De novo biosynthesis of antimycobacterial agent geranylgeranyl acetate from glucose

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Published in 2019 at "Biochemical Engineering Journal"

DOI: 10.1016/j.bej.2018.11.008

Abstract: Abstract Geranylgeranyl acetate have been identified as potent and selective inhibitors against Mycobacterium tuberculosis. In this study, the MVA pathway was engineered in Escherichia coli to biosynthesis of the antimycobacterial agent geranylgeranyl acetate from glucose… read more here.

Keywords: agent geranylgeranyl; geranylgeranyl; acetate glucose; biosynthesis antimycobacterial ... See more keywords