Metabolism of hyperpolarized 13C‐acetoacetate to β‐hydroxybutyrate detects real‐time mitochondrial redox state and dysfunction in heart tissue
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DOI: 10.1002/nbm.4091
Abstract: Mitochondrial dysfunction is considered to be an important component of many metabolic diseases yet there is no reliable imaging biomarker for monitoring mitochondrial damage in vivo. A large prior literature on inter‐conversion of β‐hydroxybutyrate and… read more here.
Keywords: mitochondrial redox; redox state; acetoacetate; hydroxybutyrate ... See more keywords
Synthesis and ionic conductivity of siloxane based polymer electrolytes with pendant propyl acetoacetate groups
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DOI: 10.1515/pac-2017-0805
Abstract: Abstract Hydrosilylation reaction of 2.4.6.8-tetrahydro-2.4.6.8-tetramethylcyclotetrasiloxane (D4H) with allyl acetoacetate at 1:4.1 molar ratios of initial compounds in the presence of platinum hydrochloric acid (0.1 M solution in THF), Karstedt’s catalyst (Pt2[(VinSiMe2)2O]3) and platinum on the… read more here.
Keywords: ionic conductivity; acetoacetate; acetoacetate groups; propyl acetoacetate ... See more keywords
Enzymatic Synthesis of New Acetoacetate–Ursodeoxycholic Acid Hybrids as Potential Therapeutic Agents and Useful Synthetic Scaffolds as Well
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DOI: 10.3390/molecules29061305
Abstract: Ursodeoxycholic acid (UDCA) and acetoacetate are natural compounds present in the human intestine and blood, respectively. A number of studies highlighted that besides their well-known primary biological roles, both compounds possess the ability to influence… read more here.
Keywords: ursodeoxycholic acid; isolated yield; acetoacetate; acetoacetoxy udca ... See more keywords