Acyl and Decarbonylative Suzuki Coupling of N-Acetyl Amides: Electronic Tuning of Twisted, Acyclic Amides in Catalytic Carbon–Nitrogen Bond Cleavage
Sign Up to like & getrecommendations! Published in 2018 at "ACS Catalysis"
DOI: 10.1021/acscatal.8b02815
Abstract: We report the Pd-catalyzed acyl and the Ni-catalyzed biaryl Suzuki–Miyaura cross-coupling of N-acetyl-amides with arylboronic acids by selective N–C(O) cleavage. Activation of the amide bond by N-acylation provides electronically destabilized, acyclic, nonplanar amide, which readily… read more here.
Keywords: bond; coupling acetyl; suzuki; acetyl amides ... See more keywords