Acetyl-L-carnitine: An effective antioxidant against cryo-damage on human spermatozoa with asthenospermia
Sign Up to like & getrecommendations! Published in 2017 at "Current Medical Science"
DOI: 10.1007/s11596-017-1827-4
Abstract: A variety of natural and artificial cryoprotectant extenders have been explored to enhance sperm recovery following cryopreservation-thawing process. The current investigation is aimed at evaluating the effect of acetyl-L-carnitine on human spermatozoa and reactive species… read more here.
Keywords: group group; acetyl carnitine; group; human spermatozoa ... See more keywords
Acetyl-l-Carnitine Attenuates Arsenic-Induced Oxidative Stress and Hippocampal Mitochondrial Dysfunction
Sign Up to like & getrecommendations! Published in 2017 at "Biological Trace Element Research"
DOI: 10.1007/s12011-017-1210-0
Abstract: Augmentation of mitochondrial oxidative stress through activating a series of deadly events has implicated as the main culprit of arsenic toxicity and therapeutic approaches based on improving mitochondrial function hold a great promise for attenuating… read more here.
Keywords: acetyl carnitine; hippocampal mitochondrial; induced oxidative; arsenic induced ... See more keywords
Acetyl-l-carnitine is an anti-angiogenic agent targeting the VEGFR2 and CXCR4 pathways.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.04.018
Abstract: Carnitines play an important role in the energy exchange in cells, and are involved in the transport of fatty acids across the inner mitochondrial membrane. l-Acetylcarnitine (ALCAR) is an acetic acid ester of carnitine that… read more here.
Keywords: acetyl carnitine; anti; alcar; cancer ... See more keywords
Acetyl-l-carnitine partially prevents benzene-induced hematotoxicity and oxidative stress in C3H/He mice.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2017.02.013
Abstract: Benzene is an environmental pollutant and occupational toxicant which induces hematotoxicity. Our previous metabonomics study suggested that acetyl-l-carnitine (ALCAR) decreased in the mouse plasma and bone marrow (BM) cells due to benzene exposure. In the… read more here.
Keywords: acetyl carnitine; benzene induced; c3h mice; alcar ... See more keywords
Comparison of the therapeutic effects of erythropoietin and acetyl-l-carnitine on sciatic nerve injury in rats
Sign Up to like & getrecommendations! Published in 2022 at "Neurological Research"
DOI: 10.1080/01616412.2022.2029293
Abstract: ABSTRACT Aim We aimed to investigate the effects of erythropoietin, acetyl-l-carnitine, and their combination on nerve regeneration in experimental peripheral nerve injury. Methods Rats were randomly divided into five groups – sham-operated (S), sciatic nerve… read more here.
Keywords: sciatic nerve; alcar; epo alcar; acetyl carnitine ... See more keywords
The efficacy of combined l‐carnitine and l‐acetyl carnitine in men with idiopathic oligoasthenoteratozoospermia: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2019 at "Andrologia"
DOI: 10.1111/and.13470
Abstract: The purpose of our analysis is to identify the effect of l‐carnitine (LC) and l‐acetyl carnitine (LAC) on the semen parameters of men with idiopathic oligoasthenoteratozoospermia (iOAT). We performed a comprehensive search to ascertain all… read more here.
Keywords: acetyl carnitine; men idiopathic; idiopathic oligoasthenoteratozoospermia; carnitine acetyl ... See more keywords
A comparative study of acetyl-l-carnitine and caloric restriction impact on hippocampal autophagy, apoptosis, neurogenesis, and astroglial function in AlCl3-induced Alzheimer's in rats.
Sign Up to like & getrecommendations! Published in 2023 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2022-0304
Abstract: Alzheimer's disease (AD) is a worldwide chronic progressive neurodegenerative disease. We aimed to investigate and compare the neuroprotective impact of acetyl-l-carnitine and caloric restriction (CR) on AlCl3-induced AD to explore the pathogenesis and therapeutic strategies… read more here.
Keywords: caloric restriction; acetyl carnitine; carnitine caloric; alcl3 ... See more keywords
Acetyl-L-carnitine can slow the progression from prefrailty to frailty in older subjects. A randomized interventional clinical trial.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical design"
DOI: 10.2174/1381612828666220830092815
Abstract: BACKGROUND The elderly is characterized by a gradual decline in body function, which represents the clinical situation called "frailty". Prefrailty is the intermediate stage between frailty and the robust condition. L-carnitine (LC) plays an important… read more here.
Keywords: acetyl carnitine; prefrailty; group; treatment ... See more keywords
Acetyl-L-Carnitine in Dementia and Other Cognitive Disorders: A Critical Update
Sign Up to like & getrecommendations! Published in 2020 at "Nutrients"
DOI: 10.3390/nu12051389
Abstract: Several studies explored the effects of acetyl-L-carnitine (ALC) in dementia, suggesting a role in slowing down cognitive decline. Nevertheless, in 2003 a systematic review concluded there was insufficient evidence to recommend a clinical use, although… read more here.
Keywords: acetyl carnitine; dementia; carnitine dementia; disorders critical ... See more keywords
OCTN2-Mediated Acetyl-l-Carnitine Transport in Human Pulmonary Epithelial Cells In Vitro
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics11080396
Abstract: The carnitine transporter OCTN2 is associated with asthma and other inflammatory diseases. The aims of this work were (i) to determine carnitine uptake into freshly isolated human alveolar type I (ATI)-like epithelial cells in primary… read more here.
Keywords: acetyl carnitine; epithelial cells; carnitine uptake; carnitine transport ... See more keywords
Supplementation with L-carnitine rescues sperm epigenetic changes in asthenospermic male semen with altered acetyl-L-carnitine levels
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive and Developmental Medicine"
DOI: 10.4103/2096-2924.294314
Abstract: Objective: To investigate the relationship between the concentration of L-carnitine in semen and sperm parameters and investigate the epigenetic profile in sperm cell after L-carnitine usage. Methods: From February 2017 to February 2018, 46 semen… read more here.
Keywords: acetyl carnitine; methylation; semen samples; dfi ... See more keywords