HPLC purification technique: synthesis of unsymmetrical thiobarbituric acids
Sign Up to like & getrecommendations! Published in 2019 at "Heliyon"
DOI: 10.1016/j.heliyon.2019.e02008
Abstract: Synthesis of thiobarbituric acids by the reaction of 1,3-disubstituted thioureas and malonic acid in acetyl chloride-acetic acid medium and synthesis of cyclized pyrimidin-7-one by the interaction of 1-(2-hydroxyethyl)-aryl thioureas, with malonic acid in p-tolyl sulphonic… read more here.
Keywords: thiobarbituric acids; purification technique; hplc purification; acetyl chloride ... See more keywords
One pot conversion of acetyl chloride to dehydroacetic acid and its coordination in a ruthenium(II) arene complex
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2017.08.003
Abstract: Abstract The reaction of [(η6-p-cymene)RuCl(κ2N,O- l- serinate)], 1, with CH3C(O)Cl/NEt3, in chloroform at reflux temperature, led to the serendipitous isolation of the dehydroacetate complex [(η6-p-cymene)RuCl(κ2O,O′-dha)], 2, in low amount. Then, dehydroacetic acid (dhaH) was prepared… read more here.
Keywords: one pot; chemistry; acetyl chloride; cymene ... See more keywords
Ultrasensitive HPLC-MS Quantification of S-(2-Succino) Cysteine Based on Ethanol/Acetyl Chloride Derivatization in Fumarate Accumulation Cells.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03573
Abstract: Succination is a nonenzymatic and irreversible post-translational modification (PTM) with important biological significance, yielding S-(2-succino) cysteine (2SC) residue. This PTM is low in abundance and often requires a large amount of protein samples for 2SC… read more here.
Keywords: fumarate accumulation; based ethanol; quantification; ethanol acetyl ... See more keywords
Utilization of cyanoacetohydrazide and 2-(1,3-dioxoisoindolin-2-yl) acetyl chloride in the synthesis of some novel anti-proliferative heterocyclic compounds
Sign Up to like & getrecommendations! Published in 2020 at "Synthetic Communications"
DOI: 10.1080/00397911.2020.1786125
Abstract: Abstract Owing to its high reactivity and commercial availability, 2-cyanoacetohydrazide can be utilized as a versatile and appropriate intermediate for synthesis of a broad variety of heterocyclic compounds. Thus, 2-cyanoacetohydrazide and 2-(1,3-dioxoisoindolin-2-yl) acetyl chloride were… read more here.
Keywords: anti proliferative; heterocyclic compounds; acetyl chloride; cyanoacetohydrazide dioxoisoindolin ... See more keywords