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Published in 2020 at "Journal of separation science"
DOI: 10.1002/jssc.202000672
Abstract: The aim of this study was to establish and validate an alternative high-performance liquid chromatography (HPLC) method for simultaneous quantification of pyrazinamide, isoniazid, acetyl-isoniazid and rifampicin in plasma of patients under treatment for tuberculosis. The…
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Keywords:
isoniazid acetyl;
method;
acetyl isoniazid;
quantification ... See more keywords
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Published in 2019 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dky378
Abstract: Objectives To describe the pharmacokinetics of isoniazid and acetyl-isoniazid in TB/HIV-coinfected patients, and assess the effects of efavirenz co-administration and a 50% increase in the dose of rifampicin on the pharmacokinetic parameters of isoniazid and…
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Keywords:
dose rifampicin;
isoniazid;
isoniazid acetyl;
pharmacokinetics isoniazid ... See more keywords