Programmed ubiquitin acetylation using genetic code expansion reveals altered ubiquitination patterns
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13702
Abstract: Ubiquitination is a post‐translational modification (PTM) capable of being regulated by other PTMs, including acetylation. However, the biological consequences of acetylated ubiquitin (acUb) variants are poorly understood, due to their transient nature in vivo and… read more here.
Keywords: code expansion; acetylation; ubiquitination patterns; using genetic ... See more keywords
An enriched environment improves maternal sleep deprivation-induced cognitive deficits and synaptic plasticity via hippocampal histone acetylation.
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.3018
Abstract: INTRODUCTION Growing evidence clearly demonstrates that maternal rodents exposure to sleep deprivation (SD) during late pregnancy impairs learning and memory in their offspring. Epigenetic mechanisms, particularly histone acetylation, are known to be involved in synaptic… read more here.
Keywords: memory; synaptic plasticity; acetylation; histone acetylation ... See more keywords
Effect of a solvent‐free acetylation treatment on reinforcements permeability and tensile behaviour of flax/epoxy and flax/wood fibre/epoxy composites
Sign Up to like & getrecommendations! Published in 2017 at "Canadian Journal of Chemical Engineering"
DOI: 10.1002/cjce.22777
Abstract: Acetylation is a common way to enhance interfacial adhesion between natural fibres and polymeric matrices in composites. This work investigates the effect of a solvent-free environmentally friendly acetylation treatment of short flax and kraft fibres… read more here.
Keywords: flax; acetylation; treatment; permeability ... See more keywords
Rutin increases alpha-tubulin acetylation via histone deacetylase 6 inhibition.
Sign Up to like & getrecommendations! Published in 2022 at "Drug development research"
DOI: 10.1002/ddr.21927
Abstract: Microtubules are dynamic cytoskeletal filaments composed of alpha- (α) and beta (β)-tubulin proteins. α-tubulin proteins are posttranslationally acetylated, and loss of acetylation is associated with axonal transport defects, a common alteration contributing to the pathomechanisms… read more here.
Keywords: tubulin acetylation; increases alpha; inhibition; rutin increases ... See more keywords
miR‐34a Targets HDAC1‐Regulated H3K9 Acetylation on Lipid Accumulation Induced by Homocysteine in Foam Cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26126
Abstract: Hyperhomocysteinemia (HHcy) promotes atherogenesis by modification of histone acetylation patterns and regulation of miRNA expression while the underlying molecular mechanisms are not well known. In this study, we investigated the effects of homocysteine (Hcy) on… read more here.
Keywords: accumulation; acetylation; mir 34a; expression ... See more keywords
Coordinated expression of p300 and HDAC3 upregulates histone acetylation during dentinogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29470
Abstract: Cellular differentiation is caused by highly controlled modifications in the gene expression but rarely involves a change in the DNA sequence itself. Histone acetylation is a major epigenetic factor that adds an acetyl group to… read more here.
Keywords: dentinogenesis; histone acetylation; acetylation; odontoblast differentiation ... See more keywords
HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia‐like animals
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25914
Abstract: Although histone acetylation is one of the most widely studied epigenetic modifications, there is still a lack of information regarding how the acetylome is regulated during brain development and pathophysiological processes. We demonstrate that the… read more here.
Keywords: h3k9; schizophrenia like; acetylation; differentiation ... See more keywords
CBP‐triggered KDM2B acetylation accelerates the carcinogenesis of colon cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29196
Abstract: Lysine (K)‐specific demethylase 2B (KDM2B) has been testified to be an oncogene in diverse cancers, which joins in mediating the carcinogenesis of cancers. Nonetheless, the function of KDM2B in colon cancer remains unexplored. The study… read more here.
Keywords: kdm2b acetylation; colon cancer; acetylation; carcinogenesis ... See more keywords
Acetyl‐CoA synthases are essential for maintaining histone acetylation under metabolic stress during zygotic genome activation in pigs
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30355
Abstract: ACSS1/2 converts acetate into acetyl‐coenzyme A, which contributes to histone acetylation in the mitochondria and cytoplasm. Zygotic genome activation (ZGA) is critical for embryo development involving drastic histone modification. An efficient crRNAs‐Cas13a targeting strategy was… read more here.
Keywords: acss1; histone acetylation; acetylation; metabolic stress ... See more keywords
Acetylome analysis of lysine acetylation in the plant pathogenic bacterium Brenneria nigrifluens
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DOI: 10.1002/mbo3.952
Abstract: Protein lysine acetylation, a dynamic and reversible posttranslational modification, plays a crucial role in several cellular processes, including cell cycle regulation, metabolism, enzymatic activities, and protein interactions. Brenneria nigrifluens is a pathogen of walnut trees… read more here.
Keywords: acetylation; analysis; brenneria nigrifluens; acetylation plant ... See more keywords
Stimulation of Fas/FasL‐mediated apoptosis by luteolin through enhancement of histone H3 acetylation and c‐Jun activation in HL‐60 leukemia cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22807
Abstract: Luteolin (3′,4′,5,7‐tetrahydroxyflavone), which exists in fruits, vegetables, and medicinal herbs, is used in Chinese traditional medicine for treating various diseases, such as hypertension, inflammatory disorders, and cancer. However, the gene‐regulatory role of luteolin in cancer… read more here.
Keywords: histone acetylation; acetylation; jun; fas fasl ... See more keywords