Sensitive and reversible perylene derivative-based fluorescent probe for acetylcholinesterase activity monitoring and its inhibitor.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2020.113835
Abstract: A reversible fluorescence probe for acetylcholinesterase activity detection was developed based on water soluble perylene derivative, N,N'-di(2-aspartic acid)-perylene-3,4,9,10-tetracarboxylic diimide (PASP). Based on the photo-induced electron transfer (PET), PASP fluorescence in aqueous is quenched after combining… read more here.
Keywords: acetylcholinesterase; probe; acetylcholinesterase activity; probe acetylcholinesterase ... See more keywords
Influence of nanoencapsulated lutein on acetylcholinesterase activity: In vitro determination, kinetic parameters, and in silico docking simulations.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2019.125523
Abstract: Lutein is a bioactive found in dark leafy vegetables that may be used as a nutraceutical agent in foodstuff and an inhibitor of key enzymes of the human body such as those involved in the… read more here.
Keywords: acetylcholinesterase; silico docking; nanoencapsulated lutein; acetylcholinesterase activity ... See more keywords
Evaluation of antioxidant and inhibitory properties of Citrus aurantium L. on the acetylcholinesterase activity and the production of amyloid nano-bio fibrils.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.04.043
Abstract: The blossoms of Citrus aurantium are considered for the treatment of Alzheimer's disease because of their fragrant essential oils. The aim of this study was to investigate the antioxidant and inhibitory effects of Citrus aurantium… read more here.
Keywords: production; inhibitory properties; production amyloid; acetylcholinesterase activity ... See more keywords
Toxicity evaluation of two polyoxotungstates with anti‐acetylcholinesterase activity
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2017.08.010
Abstract: ABSTRACT A toxicity evaluation of two Keggin‐type heteropolytungstates, K7[Ti2PW10O40]·6H2O and K6H[SiV3W9O40]·3H2O, with different inhibitory potencies toward acetylcholinesterase activity (IC50 values of 1.04 × 10− 6 and 4.80 × 10− 4 mol/L, respectively) was performed. Wistar… read more here.
Keywords: two polyoxotungstates; evaluation two; toxicity evaluation; acetylcholinesterase ... See more keywords
Colorimetric Assay for Acetylcholinesterase Activity and Inhibitor Screening Based on Metal-Organic Framework Nanosheets.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03290
Abstract: Alzheimer's disease (AD) is a common chronic neurodegenerative disease that manifests as cognitive impairment and behavioral deficits and severely threatens the health of the elderly. Acetylcholinesterase (AChE) plays a vital role in biological signaling and… read more here.
Keywords: acetylcholinesterase activity; organic framework; metal organic; activity ... See more keywords
Effects of tannic acid in streptozotocin-induced sporadic Alzheimer's Disease: insights into memory, redox status, Na+, K+-ATPase and acetylcholinesterase activity.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of physiology and biochemistry"
DOI: 10.1080/13813455.2019.1673430
Abstract: The aim of this study was to investigate the ability of tannic acid (TA) in preventing memory deficits and neurochemical alterations observed in a model for Sporadic Dementia of Alzheimer's Type. Rats were treated with… read more here.
Keywords: tannic acid; sporadic alzheimer; acetylcholinesterase activity; activity ... See more keywords