Isoquinoline Alkaloid Contents in Macleaya cordata Extracts and Their Acetylcholinesterase and Butyrylcholinesterase Inhibition
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DOI: 10.3390/molecules27113606
Abstract: An important strategy for treating neurodegenerative disorders is to maintain the levels of acetylcholine in the synaptic cleft by blocking the cholinesterases. Searching for new effective compounds with inhibited acetylcholinesterase and butyrylcholinesterase activity is one… read more here.
Keywords: inhibition; macleaya cordata; activity; cordata extracts ... See more keywords
Biologically Potent Benzimidazole-Based-Substituted Benzaldehyde Derivatives as Potent Inhibitors for Alzheimer’s Disease along with Molecular Docking Study
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DOI: 10.3390/ph16020208
Abstract: Twenty-one analogs were synthesized based on benzimidazole, incorporating a substituted benzaldehyde moiety (1–21). These were then screened for their acetylcholinesterase and butyrylcholinesterase inhibition profiles. All the derivatives except 13, 14, and 20 showed various inhibitory… read more here.
Keywords: compound; substituted benzaldehyde; butyrylcholinesterase; acetylcholinesterase butyrylcholinesterase ... See more keywords