Comparative investigation of two methods for Acetylcholinesterase enzyme immobilization on modified porous silicon
Sign Up to like & getrecommendations! Published in 2017 at "Applied Surface Science"
DOI: 10.1016/j.apsusc.2016.12.169
Abstract: Abstract In this work, Acetylcholinesterase enzyme (AChE) was immobilized on porous silicon (PSi) surface using two strategies. In the first method, acid chains were covalently grafted on the hydrogenated PSi by hydrosilylation reaction. The obtained… read more here.
Keywords: surface; comparative investigation; porous silicon; reaction ... See more keywords
2D & 3D-QSAR Study on Novel Piperidine and Piperazine Derivatives as Acetylcholinesterase Enzyme Inhibitors.
Sign Up to like & getrecommendations! Published in 2018 at "Current computer-aided drug design"
DOI: 10.2174/1573409914666180726092800
Abstract: INTRODUCTION Acetylcholinesterase enzyme (AChE) is the main target in Alzheimer's disease therapy and designing of novel AChE inhibitors is a great deal of attention. METHODS In this study, 2D-QSAR and 3D-QSAR models were generated using… read more here.
Keywords: study novel; piperazine derivatives; novel piperidine; piperidine piperazine ... See more keywords