Meta-analytic Techniques to Assess the Association Between N-acetylcysteine and Acute Kidney Injury After Contrast Administration
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.20671
Abstract: This systematic review and meta-analysis of N-acetylcysteine for the prevention of contrast-imaging acute kidney injury explores the heterogeneity, publication bias, and small study effect to determine the most suitable analytic method in a setting where… read more here.
Keywords: acute kidney; contrast; kidney injury; acetylcysteine ... See more keywords
Ameliorative effect of N‐acetylcysteine on the testicular tissue of adult male albino rats after glyphosate‐based herbicide exposure
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22997
Abstract: Glyphosate (GLP) is a broad‐spectrum herbicide that is frequently used in crop production, but its residues remain in foodstuffs. This, in turn, has led to potential adverse effects on both human and animal health. Recent… read more here.
Keywords: glp; acetylcysteine; ameliorative effect; toxicity ... See more keywords
N-acetylcysteine as a therapeutic extract for cardiac, lung, intestine and spleen injuries induced by microcystin-LR in mice
Sign Up to like & getrecommendations! Published in 2020 at "Journal of King Saud University - Science"
DOI: 10.1016/j.jksus.2019.06.001
Abstract: Abstract N-acetylcysteine (NAC) is antioxidant product that improves its function by scavenges of free oxygen radical and production of reduced glutathione (GSH). It is used in treatment of different inflammatory diseases and cancers. Subjects and… read more here.
Keywords: extract cardiac; cardiac lung; acetylcysteine; therapeutic extract ... See more keywords
N-acetylcysteine increases dopamine release and prevents the deleterious effects of 6-OHDA on the expression of VMAT2, α-synuclein, and tyrosine hydroxylase
Sign Up to like & getrecommendations! Published in 2024 at "Neurological Research"
DOI: 10.1080/01616412.2024.2325312
Abstract: ABSTRACT Objectives Current treatments for Parkinson’s disease using pharmacological approaches alleviate motor symptoms but do not prevent neuronal loss or dysregulation of dopamine neurotransmission. In this article, we have explored the molecular mechanisms underlying the… read more here.
Keywords: dopamine; acetylcysteine; vmat2 synuclein; tyrosine hydroxylase ... See more keywords
Triple A Syndrome: Preliminary Response to the Antioxidant N-Acetylcysteine Treatment in a Child
Sign Up to like & getrecommendations! Published in 2017 at "Hormone Research in Paediatrics"
DOI: 10.1159/000465520
Abstract: Introduction: Triple A syndrome (AAAS) is a rare autosomal recessive disorder characterized by alacrima, achalasia, ACTH-resistant adrenal insufficiency, autonomic dysfunction, and progressive neurodegeneration. Increased oxidative stress, demonstrated in patients’ fibroblasts in vitro, may be a… read more here.
Keywords: increased oxidative; acetylcysteine; triple syndrome; treatment ... See more keywords
Effect of N-acetylcysteine on exacerbations of bronchiectasis (BENE): a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2019 at "Respiratory Research"
DOI: 10.1186/s12931-019-1042-x
Abstract: BackgroundN-acetylcysteine is a classic mucolytic agent. This study aimed to investigate the efficacy of N-acetylcysteine on reducing the risk of exacerbations in bronchiectasis patients.MethodsA prospective, randomized, controlled trial was conducted between April 1, 2014 and… read more here.
Keywords: trial; acetylcysteine; randomized controlled; acetylcysteine group ... See more keywords
Voltammetric behavior of Zinc hexacyanoferrate (III) nanoparticles and their application in the detection of N-acetylcysteine
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Electrochemical Science"
DOI: 10.20964/2017.08.06
Abstract: The present work reports the voltammetric behavior of Zinc hexacyanoferrate (III) nanoparticles and their application in the detection of N-acetylcysteine. Two distinct ratios of water/formamide 10:0 (ZnH-1) and 4:6 (ZnH-2) were studied in the complexation… read more here.
Keywords: iii; znh; acetylcysteine; behavior zinc ... See more keywords
The Emerging Role of N-Acetylcysteine in Psychiatry: A Narrative Review of Available Data.
Sign Up to like & getrecommendations! Published in 2025 at "Current medicinal chemistry"
DOI: 10.2174/0109298673365458250901115725
Abstract: N-acetylcysteine (NAC), a cysteine derivative with a reactive thiol group, possesses antioxidant and anti-inflammatory properties. Its redox activity plays a central role in scavenging reactive oxygen and nitrogen species and modulating cellular signaling pathways. Recent… read more here.
Keywords: disorder; role; acetylcysteine; narrative review ... See more keywords
Efficacy and safety of acetylcysteine for the prevention of liver injury in COVID-19 intensive care unit patients under treatment with remdesivir
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology and Hepatology From Bed to Bench"
DOI: 10.22037/ghfbb.v15i3.2565
Abstract: Aim: The present double-blinded placebo-controlled randomized clinical trial evaluated prophylactic use of acetylcysteine for the prevention of liver injury in patients with severe COVID-19 pneumonia under treatment with remdesivir. Background: Liver injury is reportedly common… read more here.
Keywords: acetylcysteine; liver injury; treatment remdesivir; acetylcysteine prevention ... See more keywords
Sex Differences in X-ray-Induced Endothelial Damage: Effect of Taurine and N-Acetylcysteine
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox12010077
Abstract: Ionizing radiation (IR) can induce some associated pathological conditions due to numerous cell damages. The influence of sex is scarcely known, and even less known is whether the effect of antioxidants is sex-dependent. Given the… read more here.
Keywords: acetylcysteine; effect; damage; irradiated cells ... See more keywords
N-Acetylcysteine Reduced Ischemia and Reperfusion Damage Associated with Steatohepatitis in Mice
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21114106
Abstract: N-acetylcysteine (NAC) is a pharmacological alternative with great potential for reducing the deleterious effects of surgical procedures on patients with steatohepatitis. We evaluated the effect of NAC on hepatic ischemia/reperfusion (I/R) injury in C57BL/6J mice,… read more here.
Keywords: acetylcysteine; group; steatohepatitis; mice ... See more keywords