Solid phase wax coating of N-acetylcysteine (NAC) to decrease its solubility profile as a ready to mix supplement
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d1ra09279k
Abstract: N-Acetylcysteine (NAC) has health benefits attributed to its antioxidant properties and disulfide bond cleavage ability. Unfortunately, solutions of NAC are acidic with an undesirable taste and an unpleasant aftertaste. A method for slowing NAC release… read more here.
Keywords: acetylcysteine nac; phase wax; wax coating; wax ... See more keywords
In vitro analysis of n-acetylcysteine (NAC) interference with the international normalized ratio (INR).
Sign Up to like & getrecommendations! Published in 2021 at "Clinical toxicology"
DOI: 10.1080/15563650.2021.1979232
Abstract: BACKGROUND Previous literature suggests a laboratory interference of n-acetylcysteine (NAC) with prothrombin time (PT) and the international normalized ratio (INR). Early publications focused on this interaction in the setting of an acetaminophen overdose and evaluated… read more here.
Keywords: inr; interference; acetylcysteine nac; mcg ... See more keywords
Investigation of the Possible Protective Effect of N-Acetylcysteine (NAC) against Irinotecan (CPT-11)-Induced Toxicity in Rats
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DOI: 10.3390/antiox11112219
Abstract: Irinotecan (CPT-11) is a chemotherapeutic agent involved in the treatment regimens for several malignancies such as colorectal cancer. N-acetylcysteine (NAC) is a strong antioxidant and anti-inflammatory agent used in the treatment of several diseases related… read more here.
Keywords: effect; acetylcysteine nac; cpt; toxicity rats ... See more keywords
Stability of N-Acetylcysteine (NAC) in Standardized Pediatric Parenteral Nutrition and Evaluation of N,N-Diacetylcystine (DAC) Formation
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DOI: 10.3390/nu12061849
Abstract: The ESPGHAN/ESPEN/ESPR-Guidelines on pediatric parenteral nutrition (PPN) recommend the administration of the semiessential amino acid (AA) cysteine to preterm neonates due to their biochemical immaturity resulting in an inability to sufficiently synthetize endogenous cysteine. The… read more here.
Keywords: parenteral nutrition; pediatric parenteral; dac; cysteine ... See more keywords
The Synergistic Protective Effect of γ-Oryzanol (OZ) and N-Acetylcysteine (NAC) against Experimentally Induced NAFLD in Rats Entails Hypoglycemic, Antioxidant, and PPARα Stimulatory Effects
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DOI: 10.3390/nu15010106
Abstract: This study estimated that the combined effect of γ-Oryzanol and N-acetylcysteine (NAC) against high-fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) in rats also estimated some of their mechanisms of action. Adult male rats were… read more here.
Keywords: oryzanol; hfd; oryzanol acetylcysteine; acetylcysteine nac ... See more keywords
Repositioning N-Acetylcysteine (NAC): NAC-Loaded Electrospun Drug Delivery Scaffolding for Potential Neural Tissue Engineering Application
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12100934
Abstract: Traumatic brain injury (TBI) presents a serious challenge for modern medicine due to the poor regenerative capabilities of the brain, complex pathophysiology, and lack of effective treatment for TBI to date. Tissue-engineered scaffolds have shown… read more here.
Keywords: acetylcysteine nac; neural tissue; nac; nac loaded ... See more keywords